Polysaccharides ofPolygonatum. VI. A study of the structure of a glucomannan fromPolygonatum sewerzowii by13C NMR spectroscopy,electron microscopy,and x-radiography

A phytoecdysteroid, sileneoside D, has been isolated from the roots ofSilene brahuica Boiss. and it has been shown to be ecdysterone 3-O--D-galactopyranoside.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 741–744, November–December, 1984.     

Phytoecdysteroids of plants of the genusSilene. III. Sileneoside A — A new glycosidic ecdysteroid ofSilene brachuica

Ecdysterone (I), viticosterone E, polypodine B, and integristerone A (II) have been isolated from the epigeal part of the plantSilene brachuica Boiss. In addition to substances (I) and (II), the phytoecdysteroid sileneoside A has been isolated from the root of this plant. It has been shown that sileneoside A is ecdysterone 22-O-α-D-galactoside.     

Phytoecdysteroids of plants of the genus Silene. XVIII. 2-Deoxyecdysterone 20,22-monoacetonide from Silene brahuica

In addition to the known 2-deoxy--ecdysone, 2-deoxyecdysterone, 2-deoxy--ecdysone-22-O-acetate, ecdysterone, integristerone A, and sileneoside A, B, and C, the new ecdysteroid 2-deoxyecdysterone 20,20-monoacetonide has been isolated from the roots of the plantSilene brahuica Boiss.Institute of Chemistry of Plant Substances Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 241–244, March–April, 1991.     

Acetylacetone-formaldehyde reagent for the spectrophotometric determination of some sulfa drugs in pure and dosage forms

A new simple and sensitive spectrophotometric procedure for the determination of sulfacetamide sodium (I), sulfadiazine (II), sulfadimidine (III) and sulfathiazole (IV) is based on the reaction of the drug with acetylacetone-formaldehyde reagent to give a yellow product having _max at 400 nm. Optimization of the reaction conditions has been investigated. A linear correlation was obtained between absorbance at _max and the concentration. The Beer's law limits of I, II, III and IV are 4–80, 4–72, 4–60 and 4–80 g/ml, respectively. For more accurate results, Ringbom optimum concentration ranges were evaluated to be 6–76, 8–66, 6–56 and 8–75 g/ml for I, II, III and IV, respectively. The molar absorptivities and Sandell sensitivities for all sulfa drugs under consideration were evaluated. Relative standard deviations of 0.98, 1.07, 0.86 and 0.79% were obtained for I, II, III and IV, respectively. The method has been compared to the official method and found to be simple, accurate (t-test) and reproducible (F-test). The developed procedures were applied for bulk sulfa drugs and some of their dosage forms without interferences from additive and common prescribed drugs.     

Chrysin and its derivatives in plants of the genusScutellaria

Summary 1. A glycoside (II) identified by chrysin 7--glucopyranosiduronic acid has been isolated from the epigeal part ofScutellaria scordiifolia in a yield of 2.0–2.2%.2. A glycoside (IV), characterized as 2-methoxychrysin 7--D-glucopyranosiduronic acid has been isolated from the roots ofS. granulosa.3. This is the first time that chrysin and 2-methoxychrysin and their 7-glucuronides have been isolated from theScutellaria species mentioned.Khar'kov Scientific-Research Institute of Pharmaceutical Chemistry. Ukrainian Zonal Research Station for Medicinal Plants, Poltava. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 730–735, November–December, 1976.     

O-acylated flavonoid glycosides from the needles ofPicea obovata II. 3′- and 6′-isomers of p-coumaroylastragalin

Two monoacylated glycosides have been isolated from the needles ofPicea obovata — the previously unknown 3-p-coumaroylastragalin (I) and 6-p-coumaroylastragalin (II). It has been established that under the conditions of mild saponification and acid hydrolysis isomerization of (I) into (II) and the splitting out of the acy1 residue takes place. The position of the acy1 substituent has been shown by PMR spectroscopy using the INDOR method. The physicochemical characteristics of the acylated glycosides and of their heptaacetates are given.All-Union Scientific-Research Institute of Medicinal Plants, Moscow. Irkutsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, Moscow. I. M. Sechenov First Moscow Medical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 186–190, March–April, 1980.     

Coumarin glycosides ofHaplophyllum perforatum

From the epigeal part ofHaplophyllum perforatum we have isolated the coumarins scopoletin (I), scopoletin 7-0--D-glucopyranoside (II) and the new coumarin glycoside haploperoside A (III), mp 212–213°C, [] _D ²² –37° (c 0.24, CH₃OH). The acid hydrolysis of (III) formed (I) and the monosaccharides D-glucose and L-rhamnose. Partial hydrolysis of (III) with 10% acetic acid led to (II) and L-rhamnose. On the basis of the results of a study of UV, IR, and PMR spectra, and also periodate oxidation and polarimetric analysis the structure of 6-methoxy-7-[0--L-rhamnopyranosyl-(21)--D-glucopyranosyloxy] coumarin has been established for (III). Details of the IR, UV, PMR, and mass spectra are given.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenni, No. 2, pp. 168–172, March–April, 1980.     

Solvent extraction of thorium from nitric acid solutions using di-N-butyl sulfoxide (DBSO) in xylene

The extraction of thorium(IV) from nitric acid solutions by di-n-butyl sulfoxide (DBSO) in xylene has been investigated as a function of acid, extractant and the metal concentration. The effect of contact time and diverse ions on the extraction has been examined. Phosphate, fluoride, oxalate and perchlorate reduce the extraction to some extent. The extraction of other metal ions, especially impurities associated with thorium in ores, has been measured under optimised conditions selected for thorium extraction. Na(I), K(I), Ca(II), Sr(II), Mn(II), Fe(II), Ni(II), Zn(II), Pb(II), Al(III), Ti(IV) and Hf(IV) are not extracted. Among the stripping solutions employed for back-extraction, deionized water is found to be the best and more than 99% thorium can be back-extracted in three stages. The extracted species is supposed to be Th(NO₃)₄·2DBSO. The extraction is found to be almost independent of the thorium concentration in the range between 4.3·10^–4–4.3·10^–2M and inversely dependent upon the temperature. The values of thermodynamic functions H, G and S for extraction equilibrium have been evaluated to be –19.6±2.9 kJ·mole^–1, –18.1±2.0 kJ·mole^–1 and –5.0±2.9 J·mole^–1·K^–1, respectively.