三唑类硫醚及二硫醚化合物的合成

以2-苯基-1，2，3-三唑-4-甲酰肼为原料，合成了6个新的含连三唑和均三唑的硫醚类化合物，并经IR、^1HNMR、MS和元素分析进行了结构表征。     

二烯丙基硫醚化合物的合成

二烯丙基一硫醚（DS）,二烯丙基二硫醚（DDS）,二烯丙基三硫醚（DTS）和二烯丙基四硫醚（DTTS）等是大蒜提取液中的主要有效成分,具有十分广泛独特的生理药理活性。作者以甲酸、丙三醇为超始原料合成了这些化合物,烯丙基硫醚化合物总含量达83%,其中DDS,DTS含量分别达30%。产物均GC-MS鉴定确证。合成方法简单,原料易得,反应步骤少,实用性较强。     

用钐和催化量的氯化汞体系合成二硫醚

研究了在四氢呋喃溶液中用金属钐和催化量的氯化汞作还原本系还原硫氰酸酯制备二硫醚，产物的结构通过红外光谱和核磁共振谱所证示。     

烷基杂环芳基二硫醚类化合物的合成及抗癌活性研究

通过Bunte盐与杂环芳基硫醇反应,得到了一系列的烷基芳基二硫醚类化合物.得到的全部二硫醚类化合物对人结肠癌细胞HCT-116抑制活性进行了体外评价,发现所有化合物具有明显的体外抗肿瘤活性,其半抑制浓度IC50为4.8～17.7μg mL-1.     

无水二溴化锡的几种制备方法

二溴化锡(SnBr2)是一种重要的还原剂，广泛应用于分析化学实验中。灯泡生产也需要高纯度的SnBr2。     

一锅法合成二硫醚的简便制备过程研究

双（三氯甲基）碳酸酯与三苯基膦反应生成的二氯三苯基膦在三乙胺存在下与 硫酚（醇）反应，合成了一系列收率良好的二硫醚化合物。该过程采用“一锅法” ，操作方便，后处理简单，条件温和，提供了一条合成二硫醚的重要路线。     

取代二噁二唑硫醚及砜衍生物合成及抗菌活性

取代二噁二唑硫醚及砜衍生物合成及抗菌活性     

二茂钛苄氧基衍生物的合成及性质研究

Ｃｐ２ＴｉＣｌ２及（ＭｅＣｐ）２ＴｉＣｌ２在Ｅｔ３Ｎ或ＮａＮＨ２存在下与苄醇类化合物反应，高产率地合成了６个未见文献报道的二茂钛（Ⅳ）苄氧基衍生物，甲基二茂钛（Ⅳ）苄氧基化合物，经元素分析，ＨＮＭＲ和ＩＲ光谱确定了化合物的结构，并对其部分性质进行了讨论。     

环状多聚二硫醚化合物的合成及初步生物活性研究

通过二硫醇化合物氧化的方法合成了8个具有环状结构的多聚二硫醚化合物. 得到的化合物经IR, ¹H NMR, ¹³C NMR和HREIMS确证其结构, 部分化合物还经晶体X衍射方法验证. 通过对II型糖尿病靶标蛋白酪氨酸磷酸酯酶(PTP1B)抑制活性的分析, 发现一些化合物具有一定的PTP1B抑制活性.     

Electrooxidation of Thiols in the Presence of Halide Ions—A Facile Preparative Method for Synthesis of Disulfides

The aliphatic, aromatic and heteroaromatic disulfides were easily synthesized by the electrolysis of corresponding thiols. The electrochemical method is also convenient for synthesis of unsymmetrically substituted disulfides and “paired” synthesis of disulfide and sulfide.     

A Facile Method for the Syntheses of Dialkyl Disulfides from Sulfur Under Phase Transfer Conditions

A convenient reaction of alkyl halides with sulfur in alkaline medium has been found to afford disulfides in good to excellent isolated yield under phase transfer conditions.     

Rapid and Convenient Method for the Synthesis of Symmetrical Disulfides

Abstract

We present here the results on the use of 1,3,5-triazo-2,4,6-triphosphorine-2,2,4,4,6,6-hexachloride as an efficient promoter in the conversion of thiols to the corresponding symmetrical disulfides under solvent-free conditions. Aromatic thiols bearing electron donating and electron withdrawing groups, heteroaromatic, and alkyl thiols reacted efficiently to afford excellent yields of disulfides in short reaction times after easy work-up. Different functional groups including carboxyl, methoxy, methylthio, and halogen are tolerated.

Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfer, and Silicon and the Related Elements for the following free supplemental files: Additional figures and tables.     

A Facile Oxidation of Thiols to Disulfides Catalyzed by CoSalen

Abstract

A convenient and facile catalytic oxidation of thiols to the corresponding disulfides is described using CoSalen as the catalyst and air as the oxidizing agent. This new approach provides an efficient method for the preparation of symmetrical disulfides in high yields and under mild conditions.

[Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements for the following free supplemental resource: Spectroscopic Identification of Products 3a–3l.]     

A Facile Sonochemical Method for Synthesis of Mercury Selenide Nanostructures

Mercury selenide (HgSe) nanostructures has been achieved from N–N′-bis(salicylaldehyde)-1,2-phenylenediimino mercury [Hg(salophen)] as a new precursor. Cubic phase HgSe nanoparticles with the size of mostly 20–40 nm were produced by sonication of the Hg(salophen) precursor. The products were characterized by X-ray diffraction, transmission electron microscopy, scanning electron microscopy, photoluminescence, energy dispersive X-ray spectroscopy and Fourier transformed infrared spectroscopy. The results of this paper show that the shape and size of mercury selenide nanostructures can be controlled systematically by adjusting reaction parameters, such as the ultrasonic power, temperature, capping agent and reaction time.     

A Facile and Alternative Method for the Synthesis of Mefloquine

A convenient and facile synthesis of Meflo-quine, based on sulphoxide-Grignard approach is described.

     

A Facile Method for the Synthesis of Binary Tungsten Iodides

The preparation of tungsten iodides in large quantities is a challenge because these compounds are not accessible using an easy synthesis method. A new, remarkably efficient route is based on a halide exchange reaction between WCl₆ and SiI₄. The reaction proceeds at moderate temperatures in a closed glass vessel. The new compounds W₃I₁₂ (W₃I₈?2 I₂) and W₃I₉ (W₃I₈? I₂) containing the novel [W₃I₈] cluster are formed at 120 and 150 °C, and remain stable in air. W₃I₁₂ is an excellent starting material for the synthesis of other metal‐rich tungsten iodides. At increasing temperature these trinuclear clusters undergo self‐reduction until an octahedral tungsten cluster is formed in W₆I₁₂. The synthesis, structure, and an analysis of the bonding of compounds containing this new trinuclear tungsten cluster are presented.     

A Convenient Synthesis of Disulfides and Sulfenamides

We report the synthesis of disulfides from thiols through the use of morpholine-iodine complex. The method is yet another procedure for the preparation of the title compounds.