Two new dimeric acridone alkaloids from Glycosmis citrifolia

Two new acridone dimers, glycobismines-F (1) and -G (2), were isolated from the roots of Glycosmis citrifolia collected in Taiwan. The structures of the new compounds were determined based on spectral analysis.     

Two new alkaloids from Capparis himalayensis

Two new alkaloids, Capparin A (1) and B (2), along with seven known compounds 6-methoxyindoline-2,3-dione (3), wogonin (4), oroxylin A (5), kaempferol (6), apigenin (7), quercetin (8) and luteolin (9), were isolated from the whole plant of Capparis himalayensis. Their structures have been established on the basis of spectral methods and the structure of 1 was confirmed by X-ray crystallographic analysis.     

Two new alkaloids from Miliusa cuneata

Two new isoquinoline alkaloids, 2,10-dimethoxy-3,11-dihydroxy-5,6-dihydroprotoberberine (1) and 1,9-dihydroxy-2,11 -dimethoxy-4,5-dihydro-7-oxoaporphine (2), together with thirteen known alkaloids, were isolated from the ethanolic extracts of the stem and leaves of Miliusa cuneata (Graib). Their structures were elucidated predominantly by spectral evidence.     

Quinoline, quinazoline and acridone alkaloids

This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant, microbial and animal sources. The literature from July 2001 to June 2002 is reviewed, and 125 references are cited.     

Quinoline,quinazoline and acridone alkaloids

This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant, microbial and animal sources. The literature from July 2000 to June 2001 is reviewed, and 119 references are cited.     

Quinoline, quinazoline and acridone alkaloids

This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant, microbial and animal sources. The literature from July 2002 to June 2003 is reviewed, and 119 references are cited.     

Quinoline, quinazoline and acridone alkaloids

This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant, microbial and animal sources: 134 references are cited.     

Two new diterpene alkaloids from Delphinium chrysotrichum

Chemical investigation on the ethanol extract from the whole plants of Delphinium chrysotrichum resulted in the isolation of two new diterpene alkaloids named delphatisine A (1) and delphatisine B (2), respectively. The structures of the new compounds were deduced on the basis of their spectral data (IR, HREIMS, EIMS, 1D, 2D-NMR). This is the first report on the isolation of diterpenoid alkaloids from the D. chrysotrichum.     

Two new alkaloids from cigarette smoke condensate

Chemical constituents of MeOH extracts of cigarette smoke were studied. Two new alkaloids, named cigatin A (1), 2-(Pyridine-3-yloxy)-benzene-1',4'-diol and B (2), 2-(4-Methyl-pyridin-3-yloxy)-benzene-1',4'-diol, were isolated from a mainstream condensate of cigarette together with seven known alkaloids. Their structures were determined on the basis of spectral data and chemical methods.     

Two new indole alkaloids from Nauclea officinalis

Two new indole alkaloids,4-oxo-4,12-dihydroindolo[2,3-a]quinolizine-3-carbaldehyde(1)and 1,6,7-trihydro-indolo-[2,3- a]furan[3,4-g]quinolizine-3,4(13H)-dione(2),were isolated from Nauclea officinalis.Their structures were determined on the basis of 1D and 2D NMR spectral data.     

Two new alkaloids from Melodinus hemsleyanus Diels

Two new monoterpenoid indole alkaloids, named 14,15-dihydro-14β,15β-epoxy-10-hydroxyscandine (1) and 15α-hydroxy-meloscandonine (2), together with 12 known compounds, were isolated from the aerial parts of Melodinus hemsleyanus Diels. The structures of 1 and 2 were elucidated on the bases of 1D and 2D NMR spectra and MS. Two new compounds were evaluated for their PTP1B and Drak2 inhibitory effects, and inactivity.     

Two new alkaloids from Narcissus serotinus L

The Amaryllidaceae family is well known for the presence of an exclusive group of alkaloids with a wide range of biological activities. Narcissus serotinus L. is a plant belonging to this family and its geographical distribution is mainly located along the Mediterranean coast. In the present work, specimens collected near Casablanca (Morocco) were used to study the alkaloid content of this species. Starting with 350 g of the whole plant we used standard extraction and purification procedures to obtain fractions and compounds for GC-MS and NMR analysis. As well as five known alkaloids, we isolated two new compounds: 1-O-(3′-acetoxybutanoyl)lycorine and narseronine. The latter has been previously published, but with an erroneous structure.     

Two new pyrrolizidine alkaloids from Senecio nemorensis

Two new compounds, including petasinoside A and chloridate-[N-chloromethyl-hectorine], were isolated from Senecio nemorensis. The structures of these compounds were elucidated by spectroscopic methods including 1D and 2D NMR experiments.     

Two new benzylisoquinoline alkaloids from Papaver triniifolium

From the aerial parts of Papaver triniifolium Boiss. (Papaveraceae) collected from Erzincan (Eastern Anatolia), two new benzylisoquinoline alkaloids, miltanthoridine and miltanthoridinone were isolated. Their structures were established through the use of UV, EIMS, and NMR techniques.     

Quinoline, quinazoline and acridone alkaloids

This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant, microbial and animal sources; 115 references are cited.