Synthesis of N-benzoyl-L-daunosamine from D-threonine

The synthesis of N-benzoyl-$\text{L}$-daunosamine (14) from the C₄$\text{threo}$ aldehyde (2b), prepared from $\text{D}$-threonine, through the intermediacy of the C₇ adduct (7a) is reported     

Synthesis of t-butyldimethylsilyl enol ethers from sterically hindered ketones

Ketones react rapidly with $\text{t}$-butyldimethylsilyl triflate and amine bases to form $\text{t}$-butyldimethylsilyl enol ethers in high yields.     

Stereocontrolled (E,Z and erythro, threo) synthesis of ⊙-hydroxyallylic sulphides

All four isomers of substituted 3-alkylthio-4-hydroxybutenes have been synthesised: both the geometry of the double bond and the relative stereochemistry of the two chiral centres are controlled.     

The ipso-nitration of p-cresol

The nitration of $\text{p}$-cresol by nitric acid in aqueous sulphuric acid involves ~40% $\text{ipso}$-substitution at C^Me. The 4-methyl-4-nitrocyclohexa-2,5-dien-1-one (I) formed undergoes an acid-catalysed rearrangement to 4-methyl-2-nitrophenol.     

Advanced sedex (sensitive detector of exothermic processes)

The instrument described is suitable for the investigation of the thermal behaviour of substances and reaction mixtures under production conformable conditions; this is made possible by the sophisticated design of the sample chamber: easy stirring of the samples, measuring under any gas atmosphere and while bubbling gas through the sample, choice of the sample container and visual observation during the measurement. The control device allows the choice of one of three operational modes: constant temperature, linear increase in temperature, and adiabatic control; this permits the application of the SEDEX apparatus for a variety of methods including dynamic scanning, isoperibolic measurements, and (quasi) adiabatic studies.     

Synthesis of N-benzoyl L- and D-2,3,6-trideoxy-3-aminoxylo-hexose from non-carbohydrate precursors

The enantiomeric alcohols ($\text{2}$) and ($\text{11}$), obtained from (2$\text{R}$,3$\text{R}$) tartaric acid and, respectively, $\text{L}$-threonine, have been used to construct the C₆, enantiomeric deoxy amino sugar derivatives ($\text{7}$) and ($\text{12}$)     

Synthesis of Lobesia botrana and Spodoptera littoralis natural sex-attractants

Starting from the coupling reaction of alkyl cuprates with 1-alkynyl-2-propenyl acetates, the title compounds were prepared by short convenient syntheses.     

Stereoselective photosolvolyses of ipso-acetoxynitro-adducts of p-xylene

Diastereoisomers of 1,4-dimethyl-4-nitro-2,5-cyclohexadienyl acetate exchanged acetoxyls for alkoxyls on irradiation in alcohols to give the diastereoisomers of alkyl, 1,4-dimethyl-4-nitro-2,5-cyclohexadienyl ethers in isomer ratios of 70:30, whereas the irradiation in pentane yielded $\text{p}$-xylene.     

[2+2] Cycloaddition of benzyne to cis,trans- and cis,cis-1,5-cyclooctadiene

The relative rates of formation of $\text{cis}$ and $\text{trans}$ [2+2]cycloadducts of benzyne to $\text{cis}$, $\text{trans}$- and $\text{cis}$, $\text{cis}$-1,5-cyclooctadiene, $\text{trans}$- and $\text{cis}$-cyclooctene are discussed and properties of the adducts (e.g., their unusual hydrogenation) are described.     

Diastereoselective synthesis of N-acetyl-D,L-acosamine and N-benzoyl-D,L-ristosamine

N-Acyl derivatives of $\text{D}$,$\text{L}$-acosamine and $\text{D}$,$\text{L}$-ristosamine were synthesized with high stereo selectivity utilizing intramolecular Michael addition of γ- and δ-carbomoyloxy-α,β-unsaturated esters.     

New highly oxidized fusicoccane diterpenoids from the liverwort plagiochilaacanthophylla subsp. japonica

Four novel fusicoccane diterpenoids, fusicoplagins A, B, C, and D, have been isolated from the liverwort $\text{Plagiochila}$$\text{acanthophylla}$ subsp. $\text{japonica}$ and the structures determined by spectroscopic methods, chemical transformations, and X-ray crystallographic analysis.