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1.
Xiaoting Qin Yufei Ji Yanfei Gao Lei Yan Shuai Ding Yanqin Wang Zhiliang Liu 《无机化学与普通化学杂志》2014,640(2):462-468
Three new phenolate oxygen bridged transition metal complexes [Zn3(HL1)3(μ3‐CH3O)]·(ClO4)2(H2O)3 ( 1 ), [Ni2(HL1)2(μ1,1‐N3)(o‐vanillin)]·H2O ( 2 ), [Ni3(HL2)2(PhCOO)2(PhCOOH)2(EtOH)2] ( 3 ) have been synthesized by metal ions and potentially multidentate Schiff base ligands (H2L1 = 2‐((1‐hydroxy‐2‐methylpropan‐2‐ylimino) methyl)‐6‐methoxyphenol; H3L2 = (E)‐1‐((2‐hydroxy‐3‐methoxy‐benzylidene)amino)ethane‐1,2‐diol). All the three complexes 1 , 2 , and 3 have been characterized by elemental analysis, FT‐IR spectroscopy, and single‐crystal X‐ray diffraction studies. Crystal structures reveal that complex 1 is a trinuclear incomplete cubane‐like zinc cluster whereas complex 2 is a dinuclear nickel complex bridged by azide, and compound 3 is a trinuclear nickel complex. The luminescent property for complex 1 and magnetic behaviors for complexes 2 and 3 have been investigated. 相似文献
2.
Trávníček Zdeněk Maloň Michal Popa Igor Doležal Karel Strnad Miroslav 《Transition Metal Chemistry》2002,27(8):918-923
Nickel(II) complexes with 6-benzylaminopurine (BAP) derivatives, namely 6-(3-chlorobenzylamino)purine (HL1), 6-(4-chlorobenzylamino)purine (HL2) and 6-(4-fluorobenzylamino)purine (HL3), have been prepared and characterized by elemental analyses, i.r., u.v.–v.i.s., ES+ and FAB+ mass spectroscopy, magnetic susceptibility and conductivity measurements, and by thermal analysis. The complexes are: [Ni(L1(H2O)2Cl] · H2O, [Ni(L1)(H2O)-(NO3)] · H2O, [Ni(L2)(H2O)2Cl], [Ni(L2)(H2O)2(NO3)] · H2O, [Ni(HL2)(H2O)Cl2] · EtOH and [Ni(L3)(H2O)2Cl]. They have been tested in vitro for their possible cytotoxic activity against G-361 (human malignant melanoma), HOS (human osteogenic sarcoma), K-562 (human chronic myelogenous leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. 相似文献
3.
《印度化学会志》2021,98(10):100168
The three new Cobalt(II) complexes [Co(L1)2(H2O)2] (1), [Co(L2)2(H2O)2] (2), and [Co(L3)2(H2O)2] (3) have been synthesized by interaction of acyl pyrazolone ligands, 4-(4-chlorobenzoyl)3-methyl1-phenyl1H-pyrazole5(4H)-one (HL1), 4-(4-chlorobenzoyl)1-(3-chlorophenyl)3-methyl1H-pyrazole5(4H)-one (HL2) and 5-methyl4-(4-methylbenzoyl)2-phenyl2,4-dihydro3H-pyrazole3-one (HL3) with CoCl2.6H2O. The complexes were screened using FTIR, UV–Vis, TGA, and Single Crystal X-ray diffraction spectroscopic techniques. A relative study of the ligands’ FTIR spectra and their metal complexes reveal the formation, sifting, and disappearance of several bands during complexation. Other interpretations stipulated that these three complexes are mononuclear and exhibited octahedral geometry around Co2+.Triclinic crystal system, Distortion in Octahedral geometry, and Intermolecular hydrogen bonding confirmed by Single-crystal XRD analysis of [Co(L3)2(EtOH)2] complex. 相似文献
4.
The synthesis and characterization of new transition metal complexes of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) with 3‐(2‐hydroxynaph‐1‐ylazo)‐1,2,4‐triazole ( HL1 ) and 3‐(2‐hydroxy‐3‐carboxynaph‐1‐ylazo)‐1,2,4‐triazole ( HL2 ) have been carried out. Their structures were confirmed by elemental analyses, thermal analyses, spectral and magnetic data. The IR and 1H NMR spectra indicated that HL1 and HL2 coordinated to the metal ions as bidentate monobasic ligands via the hydroxyl O and azo N atoms. The UV‐Vis, ESR spectra and magnetic moment data revealed the formation of octahedral complexes [Mn L1 (AcO)(H2O)3] ( 1 ), [Co L1 (AcO)(H2O)3]·H2O ( 2 ), [Mn L2 (AcO)(H2O)3] ( 6 ) and [Co L2 (AcO)(H2O)3] ( 7 ), [Ni L1 (AcO)(H2O)] ( 3 ), [Zn L1 (AcO)(H2O)]·H2O ( 5 ), [Ni L2 (AcO)(H2O)] ( 8 ), [Zn L2 (AcO)(H2O)]·10H2O ( 10 ) have tetrahedral geometry, whereas [Cu L1 (AcO)(H2O)2] ( 4 ) and [Cu L2 (AcO)(H2O)2]·5H2O ( 9 ) have square pyramidal geometry.. The mass spectra of the complexes under EI‐con‐ ditions showed the highest peaks corresponding to their molecular weights, based on the atomic weights of 55Mn, 59Co, 58Ni, 63Cu and 64Zn isotopes; besides, other peaks containing other isotopes distribution of the metal. Kinetic and thermodynamic parameters of the thermal decomposition stages were computed from the thermal data using Coats‐Redfern method. HL2 and complexes 6 – 10 were found to have moderate antimicrobial activities against Staphylococcus aureus (gram positive), Escherichia coli (gram negative) and Salmonella sp bacteria, and antifungal activity against Fusarium oxysporum, Aspergillus niger and Candida albicans. Also, in most cases, metallation increased the activity compared with the free ligand. 相似文献
5.
《Journal of Coordination Chemistry》2012,65(12):2096-2109
Two new complexes, [Ni(HL1)(N3)(μ1,1N3)]2 (1) [HL1: NC5H4CH3C=NNH (C=O) NH2] and [Ni(L2)N3] (2) [HL2: NC5H4HC=N NH(C=S)NH2], have been synthesized by reaction of Ni(OAC)2·4H2O and sodium azide with HL1 and HL2 and characterized by elemental analysis, FT-IR, and UV–vis spectral studies. Single-crystal X-ray diffraction reveals that 1 is dinuclear with nickel(II) in an octahedral environment of NNO donors of HL1, two nitrogens of azide bridges and one nitrogen of terminal azide; 2 is mononuclear containing nickel(II) in a distorted square-planar environment of NNS donors of HL2 and one terminal azide. The structures of 1 and 2 have been optimized by density functional theory. The results of antimicrobial activities of ligands, 1 and 2 demonstrated that HL2 and 2 have good antimicrobial activity in contrast with HL1 and 1, related to the presence of sulfur donor in HL2. 相似文献
6.
《Journal of Coordination Chemistry》2012,65(1):3-13
Copper(II) complexes incorporating the isomeric tolyl-derivatised terpyridine ligands, 4′-p-tolyl-2,2′:6′,2′′-terpyridine (L1) and 6′-p-tolyl-2,2′:2′′,4′-terpyridine (L2) have been prepared and characterised by X-ray diffraction. The first of these is a co-crystal of type [Cu(L1)(NO3)2]·[Cu(L1)(NO3)(EtOH)]NO3·MeOH while the second is a single complex of type [Cu(L2)2(NO3)]NO3·0.5MeOH·1.5H2O. Crystallisation of a mixture of both products from ethanol/methanol (1:1) yields an unusual co-crystalline product of stoichiometry [Cu(L2)2NO3]2[Cu(L1)(NO3)2](NO3)2 whose structure was also confirmed by an X-ray stucture determination. 相似文献
7.
Linda GötzkeKerstin Gloe Katrina A. JolliffeLeonard F. Lindoy Axel HeineThomas Doert Anne JägerKarsten Gloe 《Polyhedron》2011,30(5):708-714
The interaction of di(2-picolyl)amine (1) and its secondary N-substituted derivatives, N-(4-pyridylmethyl)-di(2-picolyl)amine (2), N-(4-carboxymethyl-benzyl)-di(2-picolyl)amine (3), N-(4-carboxybenzyl)-di(2-picolyl)amine (4), N-(1-naphthylmethyl)-di(2-picolyl)amine (5), N-(9-anthracenylmethyl)-di(2-picolyl)amine (6), 1,4-bis[di(2-picolyl)aminomethyl]benzene (7), 1,3-bis[di(2-picolyl)aminomethyl]benzene (8) and 2,4,6-tris[di(2-picolyl)amino]triazine (9) with Ni(II) and/or Zn(II) nitrate has resulted in the isolation of [Ni(1)(NO3)2], [Ni(2)(NO3)2], [Ni(3)(NO3)2], [Ni(4)(NO3)2]·CH3CN, [Ni(5)(NO3)2], [Ni(6)(NO3)2], [Ni2(7)(NO3)4], [Ni2(8)(NO3)4], [Ni3(9)(NO3)6]·3H2O, [Zn(3)(NO3)2]·0.5CH3OH, [Zn(5)(NO3)2], [Zn(6)(NO3)2], [Zn(8)(NO3)2] and [Zn2(9)(NO3)4]·0.5H2O. X-ray structures of [Ni(4)(NO3)2]·CH3CN, [Ni(6)(NO3)2] and [Zn(5)(NO3)2] have been obtained. Both nickel complexes exhibit related distorted octahedral coordination geometries in which 4 and 6 are tridentate and bound meridionally via their respective N3-donor sets, with the remaining coordination positions in each complex occupied by a monodentate and a bidentate nitrato ligand. For [Ni(4)(NO3)2]·CH3CN, intramolecular hydrogen bond interactions are present between the carboxylic OH group on one complex and the oxygen of a monodentate nitrate on an adjacent complex such that the complexes are linked in chains which are in turn crosslinked by intermolecular offset π-π stacking between pyridyl rings in adjacent chains. In the case of [Ni(6)(NO3)2], two weak CH?O hydrogen bonds are present between the axial methylene hydrogen atoms on one complex and the oxygen of a monodentate nitrate ligand on a second unit such that four hydrogen bonds link pairs of complexes; in addition, an extensive series of π-π stacking interactions link individual complex units throughout the crystal lattice. The X-ray structure of [Zn(5)(NO3)2] shows that the metal centre once again has a distorted six-coordinated geometry, with the N3-donor set of N-(1-naphthylmethyl)-di(2-picolyl)amine (5) coordinating in a meridional fashion and the remaining coordination positions occupied by a monodentate and a bidentate nitrato ligand. The crystal lattice is stabilized by weak intermolecular interactions between oxygens on the bound nitrato ligands and aromatic CH hydrogens on adjacent complexes; intermolecular π-π stacking between aromatic rings is also present. 相似文献
8.
Prof. Dr. Tarlok S. Lobana Poonam Kumari Gagandeep Bawa Geeta Hundal Ray J. Butcher Francisco J. Fernandez Jerry P. Jasinski James A. Golen 《无机化学与普通化学杂志》2012,638(5):804-810
Complexes of pyrrole‐2‐carbaldehyde thiosemicarbazones, [(C4H4N4)(H)C2=N3–N2(H)–C1(=S)–N1HR; R = Ph, H2L1; Me, H2L2; H, H2L3] with nickel(II) and palladium(II) are described. The reaction of nickel(II) acetate with H2L1 in methanol in 1:1 molar ratio yielded a complex of composition, [Ni(κ2‐N3,S‐HL1)2] ( 1 ). Likewise reaction of NiCl2 with H2L2 in 1:1 molar ratio in acetonitrile in the presence of triethylamine base followed by the addition of pyridine did not yield the anticipated [Ni(κ3‐N4,N3,S‐L2)(py)] complex, moreover a bis‐square‐planar complex, [Ni(κ2‐N3,S‐HL2)2] ( 2 ) was formed. However, in the presence of bipyridine (bipy), it yielded the addition product, [Ni(κ2‐N3,S‐HL2)2(κ2‐N, N‐bipy)] ( 3 ). Reaction of PdCl2(κ2‐P, P–PPh2–CH2–PPh2) with H2L3 in toluene in the presence of triethylamine has yielded a complex of stoichiometry, [Pd(κ3‐N4,N3,S–L3)(κ1‐P–PPh2–CH2–P(O)Ph2] ( 4 ). The ligands (HL1)– and (HL2)– are chelating to NiII metal atom as anions binding through N3,S‐donor atoms with pendant pyrrole groups, and (L3)2– is chelating to the PdII metal atom as dianion through N4,N3,S‐donor atoms (pyrrole is N4‐bonded). Fourth site in 4 is bonded to one P‐donor atom of PPh2–CH2–P(O)Ph2, whose pendant –PPh2 group involves auto oxidation to –P(O)PPh2 during reaction. These complexes were characterized using analytical data, IR, NMR (1H, 31P) spectroscopy and X‐ray crystallography. Complexes 1 , 2 , and 4 have square‐planar arrangement, whereas complex 3 is octahedral. 相似文献
9.
Ten copper(II) complexes {[CuL1Cl] (1), [CuL1NO3]2 (2), [CuL1N3]2 · 2/3H2O (3), [CuL1]2(ClO4)2 · 2H2O (4), [CuL2Cl]2 (5), [CuL2N3] (6), [Cu(HL2)SO4]2 · 4H2O (7), [Cu(HL2)2] (ClO4)2 · 1/2EtOH (8), [CuL3Cl]2 (9), [CuL3NCS] · 1/2H2O (10)} of three NNS donor thiosemicarbazone ligands {pyridine-2-carbaldehyde-N(4)-p-methoxyphenyl thiosemicarbazone [HL1], pyridine-2-carbaldehyde-N(4)-2-phenethyl thiosemicarbazone [HL2] and pyridine-2-carbaldehyde N(4)-(methyl), N(4)-(phenyl) thiosemicarbazone [HL3]} were synthesized and physico-chemically characterized. The crystal structure of compound 9 has been determined by X-ray diffraction studies and is found that the dimer consists of two square pyramidal Cu(II) centers linked by two chlorine atoms. 相似文献
10.
Shyamapada Shit Joy Chakraborty Brajagopal Samanta Alexandra M. Z. Slawin Volker Gramlich Samiran Mitra 《Structural chemistry》2009,20(4):633-642
Three new coordination complexes, 2{[Co(L1)2]ClO4} · 0.5CH3OH (1), [Mn(L2)2] (2), and [Cu(HL2)(L2)]ClO4 · 2H2O (3) have been synthesized from two tridentate N,N,O-donor hydrazone ligands HL1, 2-acetylpyridine-salicyloylhydrazone, and HL2, 2-benzoylpyridine-salicyloylhydrazone, respectively and thoroughly characterized by elemental analysis, FT-IR, UV–Vis, electrochemical,
and room temperature magnetic susceptibility measurements. Structures of the complexes have been unequivocally established
by single crystal X-ray diffraction technique. Structural analysis reveals that 1 consists of two chemically similar but crystallographically independent cationic [Co(L1)2]+ units and 2 consists of a neutral [Mn(L2)2] molecule while 3 consists of a cationic [Cu(HL2)(L2)]+ unit. Metal ions display distorted octahedral geometry in 1 and 2 while in 3 it shows a distorted square pyramidal geometry. Ligand conformations around the metal ions are stabilized by the presence
of intra-ligand hydrogen bonding in all the complexes. Structure of 3 reveals that a perchlorate ion linked to the complex by hydrogen bonding via a water molecule. 相似文献
11.
《Journal of Coordination Chemistry》2012,65(6):942-951
Two new complexes, trans-[MnL2(NCS)2] (1) and trans-[CoL2(H2O)(EtOH)](ClO4)2?·?H2O (2) with asymmetrical triaryltriazole ligands [L?=?3-(p-chlorophenyl)-4-(p-methylphenyl)-5-(2-pyridyl)-1,2,4-triazole], have been synthesized and characterized by elemental analysis, FT-IR, ESI-MS, and single-crystal X-ray diffraction. In the complexes each L adopts a chelating bidentate mode via the nitrogen of pyridyl and triazole. Both complexes have a similar distorted octahedral core with two NCS? ions in the trans position in 1, while one H2O and one EtOH are present in the axial sites in 2. 相似文献
12.
《Journal of Coordination Chemistry》2012,65(13):1113-1122
Naphthaldimines containing N2O2 donor centers react with platinum(II) and (IV) chlorides to give two types of complexes depending on the valence of the platinum ion. For [Pt(II)], the ligand is neutral, [(H2L1)PtCl2]·3H2O (1) and [(H2L3)2Pt2Cl4]·5H2O (3), or monobasic [(HL2)2Pt2Cl2]·2H2O (2) and [(HL4)2Pt]·2H2O (4). These complexes are all diamagnetic having square-planar geometry. For [Pt(IV)], the ligand is dibasic, [(L1)Pt2Cl4(OH)2]·2H2O (5), [(L2)Pt3Cl10]·3H2O (6), [(L3)Pt2Cl4(OH)2]·C2H5OH (7) and [(L4)Pt2Cl6]·H2O (8). The Pt(IV) complexes are diamagnetic and exhibit octahedral configuration around the platinum ion. The complexes were characterized by elemental analysis, UV-Vis and IR spectra, electrical conductivity and thermal analyses (DTA and TGA). The molar conductances in DMF solutions indicate that the complexes are non-ionic. The complexes were tested for their catalytic activities towards cathodic reduction of oxygen. 相似文献
13.
Mononuclear nickel(II) complexes with two ONS donor thiosemicarbazone ligands {salicylaldehyde 3-hexamethyleneiminyl thiosemicarbazone [H2L1] and salicylaldehyde 3-tetramethyleneiminyl thiosemicarbazone [H2L2]} have been prepared and physico-chemically characterized. IR and electronic spectra of the complexes have been obtained. The thiosemicarbazones bind to the metal as dianionic ONS donor ligands in all the complexes except in [Ni(HL1)2] (1). In compound 1, the ligand is coordinated as a monoanionic (HL−) one. The magnetic susceptibility measurements indicate that all the complexes are mononuclear and are diamagnetic. The complexes were given the formulae [Ni(HL1)2] (1), [NiL1py] (2), [NiL1α-pic] (3), [NiL1γ-pic] · H2O (4), [NiL2py] (5) and [NiL2γ-pic] (6). The structures of compounds 2 and 3 have been solved by single crystal X-ray crystallography and were found to be distorted square planar in geometry with coordination of azomethine nitrogen, thiolato sulfur, phenolato oxygen and pyridyl nitrogen atoms. 相似文献
14.
A series of polymeric cobalt(II), nickel(II), zinc(II) and cadmium(II) azido complexes with hydrazine of the type [M(N2H4)(H2O)(N3)Cl]n, [M(N2H4)(N3)2]n and [M(N2H4)2(N3)2]n have been prepared. These were characterized by elemental analyses, magnetic susceptibility measurements, electronic and IR spectra. The complexes are highly insoluble in polar and non polar solvents. All the complexes decompose with explosion at different temperatures between 100°C to 200°C. The magnetic moment and electronic spectral data for Co(II) and Ni(II) complexes suggest that the complexes have octahedral structure. The ligand-field parameters (10 Dq, B, β, β° and LFSE) have also been calculated for all Co(II) and Ni(II) complexes which indicate a significant covalent character of M-L bonds. The IR spectra of the complexes show that the azide group and hydrazine molecule both act as bidentate bridging ligands in [M(N2H4)(H2O)(N3)Cl]n and [M(N2H4)(N3)2]n type complexes but the azide group is terminally bonded to metal in all [M(N2H4)2(N3)2]n type complexes. 相似文献
15.
Two new acylhydrazone copper(II) complexes of 4‐hydroxy‐N′‐[(1E)‐1‐(4‐methylphenyl)ethylidene]benzohydrazide (HL1) and 4 ethyl [4‐({(2E)‐2‐[1‐(4‐methylphenyl)ethylidene]hydrazinyl}carbonyl)phenoxy]acetate (HL2) have been synthesized and characterized. The structures of both acylhydrazone and copper(II) complexes were identified by elemental analysis, infrared spectra, UV–visible electronic absorption spectra, magnetic susceptibility measurements, TGA and powder X‐ray diffraction. DNA binding and DNA cleavage activities of the synthesized copper complexes were examined by using UV‐visible titration and agarose gel electrophoresis, respectively. The effect of complex concentration on the DNA cleavage reactions in the absence and presence of H2O2 was also investigated. The results indicate that all the complexes bind slightly to calf thymus DNA and cleavage pBR322 DNA. The mechanistic studies demonstrate that a hydrogen peroxide‐derived species and singlet oxygen (1O2) are the active oxidative species for DNA cleavage. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
16.
Mriganka Das Poulami Mandal Novina Malviya Indrani Choudhuri Maria Adilia Januário Charmier Susana Morgado 《Journal of Coordination Chemistry》2016,69(24):3619-3637
Three new Cu(II) complexes, [Cu(HL1)(pyridine)(H2O)](ClO4)2·2MeOH (1), [Cu2(HL1)2(NO3)2](NO3)2·3H2O (2) and [Cu(HL2)(NO3)2]·MeCN (3), have been synthesized from two Schiff base ligands [HL1 = 1-phenyl-3-((2-(piperazin-4-yl)ethyl)imino)but-1-en-1-ol and HL2 = 4-((2-(piperazin-1-yl)ethyl)imino)pent-2-en-2-ol] using the chair conformer of a flexible piperazinyl moiety. Structural analysis reveals that 1 and 3 are monomeric Cu(II) complexes consisting of five- and six-coordinate Cu(II), respectively, whereas 2 is a dinuclear Cu(II) complex consisting of two different Cu(II) centers, one square planar with the other distorted octahedral. Screening tests were conducted to quantify the binding of 1–3 towards DNA and BSA as well as the DNA cleavage activity of these complexes using gel electrophoresis. Enzyme kinetic studies were also performed for the complexes mimicking catecholase-like activities. Antibacterial activities of these complexes were also examined towards Methicillin-Resistant Staphylococcus aureus bacteria. The results reflect that 2 is more active than the monomeric complexes, which is further corroborated by density functional theory study. 相似文献
17.
Summary Copper(II), nickel(II) and cobalt(II) perchlorate complexes of 5,5-dimethylcyclohexane-1,2,3-trione-2-(p-nitrophenyl-hydrazone) (HL1), 5,5-dimethyl-cyclohexane-1,2,3-trione-2-(p-chlorophenylhydrazone) (HL2), 5,5-dimethylcyclohexane-1,2,3-trione-2-(o-chlorophenylhydrazone) (HL4), 5,5-dimethylcyclohexane-1,2,3-trione-2-(o-methylphenyl-hydrazone) (HL5) and 5,5-dimethylcyclohexane-1,2,3-trione-2-(m-methylphenylhydrazone) (HL6) have been prepared, and characterized using analytical, spectral and magnetic measurements. The data reveal that the reaction of Cu(ClO4)2 (1 mol) in EtOH, with all ligands, produces complexes of the type CuL(ClO4)(H2O).nH2O. Nickel(II) and cobalt(II) perchlorates react only with HL1 and HL2 to produce the complexes ML(ClO4)(H2O)3 (where M = NiII, L = L– and L2, M = CoII, L = L1) and Co(HL2)2-(ClO4)2.2H2O. The spectral data show that the ligands behave as monobasic bidentate in their azo forms, except HL2 which reacts with cobalt(II) as a neutral bidentate ligand in its hydrazone form. 相似文献
18.
《Journal of Coordination Chemistry》2012,65(8):1418-1429
New bi- and trihomonuclear Mn(II), Co(II), Ni(II), and Zn(II) complexes with sulfa-guanidine Schiff bases have been synthesized for potential chemotherapeutic use. The complexes are characterized using elemental and thermal (TGA) analyses, mass spectra (MS), molar conductance, IR, 1H-NMR, UV-Vis, and electron spin resonance (ESR) spectra as well as magnetic moment measurements. The low molar conductance values denote non-electrolytes. The thermal behavior of these chelates shows that the hydrated complexes lose water of hydration in the first step followed by loss of coordinated water followed immediately by decomposition of the anions and ligands in subsequent steps. IR and 1H-NMR data reveal that ligands are coordinated to the metal ions by two or three bidentate centers via the enol form of the carbonyl C=O group, enolic sulfonamide S(O)OH, and the nitrogen of azomethine. The UV-Vis and ESR spectra as well as magnetic moment data reveal that formation of octahedral [Mn2L1(AcO)2(H2O)6] (1), [Co2(L1)2(H2O)8] (2), [Ni2L1(AcO)2(H2O)6] (3), [Mn3L2(AcO)3(H2O)9] (5), [Co3L2(AcO)3(H2O)9] · 4H2O (6), [Ni3L2(AcO)3(H2O)9] · 7H2O (7), [Mn3L3(AcO)3(H2O)6] (9), [Co2(HL3)2(H2O)8] · 4H2O (10), [Ni3L3(AcO)3(H2O)9] (11), [Mn3L4(AcO)3(H2O)9] · H2O (13), [Co2(HL4)2(H2O)8] · 5H2O (14), and [Ni3L4(AcO)3(H2O)9] (15) while [Zn2L1(AcO)2(H2O)2] (4), [Zn3L2(AcO)3(H2O)3] · 2H2O (8), [Zn3L3(AcO)3(H2O)3] · 3H2O (12), and [Zn3L4(AcO)3(H2O)3] · 2H2O (16) are tetrahedral. The electron spray ionization (ESI) MS of the complexes showed isotope ion peaks of [M]+ and fragments supporting the formulation. 相似文献
19.
20.
Maruthachalam Mohanraj Ganesan Ayyannan Gunasekaran Raja Chinnasamy Jayabalakrishnan 《应用有机金属化学》2016,30(7):550-560
Three ruthenium(II) hydrazone complexes of composition [RuCl(CO)(PPh3)2L] were synthesized from the reactions of [RuHCl(CO)(PPh3)3] with hydrazones derived from 4‐methoxybenzhydrazide and 4‐formylbenzoic acid (HL1), 4‐methylbenzaldehyde (HL2) and 2‐bromobenzaldehyde (HL3). The synthesized hydrazone ligands and their metal complexes were characterized using elemental analysis and infrared, UV–visible, NMR (1H, 13C and 31P) and mass spectral techniques. The hydrazone ligands act as bidentate ones, with O and N as the donor sites, and are predominantly found in the enol form in all the complexes studied. The molecular structures of the ligands HL1, HL2 and HL3 were determined using single‐crystal X‐ray diffraction. The interactions of the ligands and the complexes with calf thymus DNA were studied using absorption spectroscopy and cyclic voltammetry which revealed that the compounds could interact with calf thymus DNA through intercalation. The DNA cleavage activity of the complexes was evaluated using a gel electrophoresis assay which revealed that the complexes act as good DNA cleavage agents. In addition, all the complexes were subjected to antioxidant assay, which showed that they all possess significant scavenging activity against 2,2‐diphenyl‐2‐picrylhydrazyl, OH and NO radicals. The in vitro cytotoxic effect of the complexes examined on cancerous cell lines (HeLa and MCF‐7) showed that the complexes exhibit substantial anticancer activity. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献