Aminoacyl derivatives of nucleosides,nucleotides, and polynucleotides

Conclusions A method for the synthesis of 3(2)-O-aminoacylnucleoside 5-di- and triphosphates has been developed which is based on the condensation of the imidazolides of N-tert-butoxycarbonylamino acids with nucleoside di-and triphosphates and subsequent removal of the tert-butoxycarbonyl protection by treatment with hydrogen chloride in absolute ether.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 1084–1087, May, 1968.     

Amino-acyl derivatives of nucleosides,nucleotides, and polynucleotides

Conclusions A new method was developed for the synthesis of 3(2)-O-(amino-acyl)nucleotides by the condensation of nucleotides with 1-[(t-butoxycarbonylamino)acyl]imidazoles with subsequent removal of the t-butoxycarbonyl protection by treatment with hydrogen chloride in dry ether.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 2, pp. 378–382, February, 1968.     

Synthesis of aminoacyl derivatives of nucleosides,nucleotides, and polynucleotides

Conclusions The possibility has been shown of extending the method of synthesis of O-aminoacyl derivatives of nucleotides and nucleoside triphosphates to prepare 3(2)-O-peptidyI-micleoside-5-triphosphates.TranslatedfromlzvestiyaAkademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1369–1372, June, 1970.     

Synthesis of 5-styryl derivatives of uracil nucleosides and nucleotides.

Uracil nucleosides and nucleotides undergo a palladium catalyzed coupling reaction with styrenes to yield the respective 5-substituted derivatives.     

Identification, separation, and quantitative analysis of derivatives of nucleosides and nucleotides by thin-layer chromatography on cellulose

Summary The thin-layer chromatography of nucleoside and nucleotide derivatives on cellulose has been carried out, and R _f values and conditions for the separation and quantitative analysis of these mixtures by this method have been given.Khimiya Frirodnykh Soedinenii, Vol. 1, No. 5, pp. 335–342, 1965