共查询到20条相似文献,搜索用时 15 毫秒
1.
Alferov K. V. Zhukov Yu. N. Khurs E. N. Osipova T. I. Khomutov R. M. 《Russian Chemical Bulletin》2001,50(2):316-318
A convenient procedure for the synthesis of 1-amino-3-hydroxypropylphosphinic and -phosphonic acids (analogs of homoserine) was developed. The procedure involves the reaction of salts of phosphinic and phosphonic analogs of S-methylmethionine with AcONa/AcOH followed by hydrolysis. 相似文献
2.
A. V. Belyankin A. R. Khomutov Yu. N. Zhukov O. N. Kartasheva R. M. Khomutov 《Russian Chemical Bulletin》1997,46(1):133-136
The reaction of aryl and aralkyl aldoximes with hypophosphorous acid resulted in aminophosphinic acids, which were oxidized
into the corresponding aminophosphonic acids.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 137–140, January, 1997. 相似文献
3.
Józef Oleksyszyn Ewa Gruszecka Paweł Kafarski Przemysław Mastalerz 《Monatshefte für Chemie / Chemical Monthly》1982,113(1):59-71
Preparation of the phosphonic analogs of -methylaspartic (4 a–d), glutamic (7 a–b) and -methylpyroglutamic (5 a–b) acids by aminoalkylation of trivalent phosphorus chlorides with ethyl esters of oxoalkyloacids and benzyl carbamate is described. The phosphonic analogs of pyroglutamic acid (8 a–b) was obtained by the cyclization of the corresponding esters (9 a–b). The stability of the phosphonic analogs of pyroglutamic acid in acidic and alkaline media was also studied.
Die Herstellung von neuen Phosphonanalogen der Asparagin- und Glutaminsäure in der Reaktion von trivalenten Phosphorchloriden mit Ethyl-acetyloacetat oder Ethyl-lävulinat bzw. Benzylcarbaminat
Zusammenfassung Es wurde die Darstellung der Phosphonanalogen der -Methylasparaginsäure (4 a–d), Glutamin- (7 a–b) und -Methylpyroglutaminsäure (5 a–b) in der Reaktion der trivalenten Phosphorchloride und der Oxoalkansäureethylester sowie des Benzylcarbaminats beschrieben. In der Ringschlußreaktion der Ester (9 a–b) erhält man Phosphonanaloge der Pyroglutaminsäure. Die Stabilität der Analogen der Pyroglutaminsäure wurde in sauren und alkalischen Medien geprüft.相似文献
4.
Yu. N. Zhukov A. R. Khomutov T. I. Osipova R. M. Khomutov 《Russian Chemical Bulletin》1999,48(7):1348-1351
Phosphinic analogs of the key compounds of the metabolism of methionine were synthesized. The compounds obtained were selectively
oxidized either at the phosphinic group or at the sulfur-containing fragment.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1360–1363, July, 1999. 相似文献
5.
Haichao Zhao Fumio Sanda Toshio Masuda 《Journal of polymer science. Part A, Polymer chemistry》2005,43(21):5168-5176
Aspartic acid‐based novel poly(N‐propargylamides), i.e., poly[N‐(α‐tert‐butoxycarbonyl)‐L ‐aspartic acid β‐benzyl ester N′‐propargylamide] [poly( 1 )] and poly[N‐(α‐tert‐butoxycarbonyl)‐L ‐aspartic acid α‐benzyl ester N′‐propargylamide] [poly( 2 )] with moderate molecular weights were synthesized by the polymerization of the corresponding monomers 1 and 2 catalyzed with (nbd)Rh+[η6‐C6H5B?(C6H5)3] in CHCl3 at 30 °C for 2 h in high yields. The chiroptical studies revealed that poly( 1 ) took a helical structure in DMF, while poly( 2 ) did not in DMF but did in CH2Cl2, CHCl3, and toluene. The helicity of poly( 1 ) and poly( 2 ) could be tuned by temperature and solvents. Poly( 2 ) underwent solvent‐driven switch of helical sense, accompanying the change of the tightness. © 2005 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 43: 5168–5176, 2005 相似文献
6.
A. N. Chekhlov 《Russian Chemical Bulletin》1992,41(11):2018-2021
The crystalline and molecular structure ofDL-2-amino-4-phosphonobutyric acid monohydrate has been studied by means of x-ray diffraction analysis. The acid molecule exists in a zwitterionic form with a deprotonated PO3H2 group. In the crystalline structure there is a branched system of intermolecular hydrogen bonding and the unusual intermolecular bond C–H...O=C forming part of it has been found.Institute of Physiologically Active Compounds, Russian Academy of Sciences, 142432 Chernogolovka. Translated fromIzvestiya Akademii Nauk, Seriya Khimicheskaya, No. 11, pp. 2561–2565, November, 1992. 相似文献
7.
QIAN Hui-Fena② HUANG Weib② LI Hui-Huib YAO Chenga a 《结构化学》2006,25(10):1243-1249
1 INTRODUCTION Chiral amino acids and their versatile derivatives are very useful compounds in many fields[1]. In com- parison with well-documented chiral α and β amino acids and amino alcohols, the studies of chiral γ, δ… ω amino acids and amino alcohols deserve more attention. For example, there have been numerous reports on versatile functions of γ aminobutyric acid (GABA) produced from L-glutamic acid in the presence of L-glutamate decarboxylase (GAD)[2]. However, the stereo… 相似文献
8.
Saikat Mandal P. R. Selvakannan Sumant Phadtare Renu Pasricha Murali Sastry 《Journal of Chemical Sciences》2002,114(5):513-520
Development of reliable protocols for the synthesis of nanoparticles of well-defined sizes and good monodispersity is an important
aspect of nanotechnology. In this paper, we present details of the synthesis of gold nanoparticles of good monodispersity
by the reduction of aqueous chloroaurate ions by the amino acid, aspartic acid. The colloidal gold solution thus formed is
extremely stable in time, indicating electrostatic stabilization via nanoparticle surface-bound amino acid molecules. This
observation has been used to modulate the size of the gold nanoparticles in solution by varying the molar ratio of chloroaurate
ions to aspartic acid in the reaction medium. Characterization of the aspartic acid-reduced gold nanoparticles was carried
out by UV-visible spectroscopy, thermogravimetric analysis and transmission electron microscopy. The use of amino acids in
the synthesis and stabilization of gold nanoparticle in water has important implications in the development of new protocols
for generation of bioconjugate materials. 相似文献
9.
2-Alkyl-3-(1-methyl-2-benzimidazolyl)-7-acyloxychromones were synthesized by the reaction of substituted or unsubstituted
2-(2,4-dihydroxyphenacyl)-1-methylbenzimidazoles with the acid chlorides and anhydrides of carboxylic acids. The products
were converted into 2-alkyl-7-hydroxychromones as a result of acid hydrolysis.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 26–30, January, 2008. 相似文献
10.
The ability of the GROMOS96 force field to reproduce partition constants between water and two less polar solvents (cyclohexane and chloroform) for analogs of 18 of the 20 naturally occurring amino acids has been investigated. The estimations of the solvation free energies in water, in cyclohexane solution, and chloroform solution are based on thermodynamic integration free energy calculations using molecular dynamics simulations. The calculations show that while the force field reproduces the experimental solvation free energies of nonpolar analogs with reasonable accuracy the solvation free energies of polar analogs in water are systematically overestimated (too positive). The dependence of the calculated free energies on the atomic partial charges was also studied. 相似文献
11.
Donald M. Kirschenbaum 《Applied biochemistry and biotechnology》1984,9(5-6):489-536
The amino acid analyses of 186 proteins are given as residues per 1000 residues. Additional information as carbohydrate composition,
content of uncomon amino acids, and sources of all proteins are also presented. 相似文献
12.
13.
Rim Benali‐Cherif Radhwane Takouachet El‐Eulmi Bendeif Nourredine Benali‐Cherif 《Acta Crystallographica. Section C, Structural Chemistry》2014,70(7):689-692
Two polymorphs of L‐aspartic acid hydrochloride, C4H8NO4+·Cl−, were obtained from the same aqueous solution. Their crystal structures have been determined from single‐crystal data collected at 100 K. The crystal structures revealed three‐ and two‐dimensional hydrogen‐bonding networks for the triclinic and orthorhombic polymorphs, respectively. The cations and anions are connected to one another via N—H...Cl and O—H...Cl interactions and form alternating cation–anion layer‐like structures. The two polymorphs share common structural features; however, the conformations of the L‐aspartate cations and the crystal packings are different. Furthermore, the molecular packing of the orthorhombic polymorph contains more interesting interactions which seems to be a favourable factor for more efficient charge transfer within the crystal. 相似文献
14.
A method of preparation of the title compound 1a avoiding the use of gaseous chlorine is described. Tetramethylthiuram disulfide 4 is oxidized with sulfuryl chloride to dime thyl thiocarbamoyl chloride 5, which is converted to 1a by means of phosphorus pentachloride. 相似文献
15.
A variety of structural types of fluorinated allylic acetates, prepared by vinylalumination of fluorinated aldehydes, were reacted with the benzophenone imine of glycine tert-butyl ester to provide 4-(fluorobenzylidenyl)- and 4-(fluoroalkylidenyl) glutamic acid derivatives in 61-96% yield. The 4-(4-fluorobenzylidenyl) glutamic acid derivative was hydrolyzed to give the 4-(4-fluorobenzylidenyl)pyroglutamate and then hydrogenated to the 4-(4-fluorobenzyl)pyroglutamate. The catalytic enantioselective conjugate addition-elimination of the benzophenone imine of glycine tert-butyl ester with the fluorinated allylic acetates prepared from fluoral, pentafluorobenzaldehyde, and 2,6-difluorobenzaldehyde provided the corresponding 4-(fluoroalkylidenyl)- and 4-(fluorobenzylidenyl) glutamic acid derivatives in 42, 45 and 80% ee, respectively. 相似文献
16.
Donald M. Kirschenbaumt 《Applied biochemistry and biotechnology》1982,7(5):343-384
The amino acid analyses of 183 proteins, as residues per 1000 residues, are given. In addition the carbohydrate content and
the content of any noncommon amino acids are also given. The sources of all proteins are presented. 相似文献
17.
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19.
Treatment of substituted 2-(2,4-dihydroxyphenacyl)thiazole and 2-(2,4-dihydroxyphenacyl)benzothiazole with propionic and isobutyric
anhydrides gives the substituted 2-ethyl-and 2-isopropyl-7-acyloxychromones. The use of pivaloyl chloride gives 1-pivaloyloxy-2-hetarylstyrene
derivatives.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 835–840, June, 2008. 相似文献
20.
Yoann Marsac Stéphanie Legoupy Muriel Pipelier Anne-Marie Aubertin Rachid Benhida 《Tetrahedron》2005,61(32):7607-7612
Enantiomerically enriched cyclobutene compounds 13 and 24 are good precursors of several cyclobutane nucleoside analogs. The synthetic ways involve, in the key step, either hydroboration or dihydroxylation. 相似文献