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1.
Xu Qin LI Kun GAO Zhong Jian JIA* College of Chemistry Chemical Engineering National Laboratory of Applied Organic Chemistry Lanzhou University Lanzhou 《中国化学快报》2002,13(10)
Chemical investigation of L.sagitta afforded two new eremophilenolides, which were identified as 6β-angeloyloxy-10β-hydroxy-8 β-methoxy-eremophil-7(11)-en-12, 8α-olide (1) and 6β, 8β-dimethoxy-10β-hydroxy-eremophil-7(11)-en-12, 8α-olide (2). Their structures were estab- lished by spectroscopic methods including 2D NMR experiments. 相似文献
2.
Ligulariajischerihasl0ngbeenusedastraditi0naImedicinet0relievec0ugh,invig0ratethecircuIation0fbIo0dandst0ppain'.FromtheplantgrowinginShengnonaiia,Hubei-Chlna,t\v0neweremophiIen0lideshavebeenisolated.Comp0undlwasneedlecrystalsfrompetr0lether(60-9O'C),m.p.=148-l50'C.ItsformulawasdeterminedasC,,H,'O'by"C-NMRandDEPTspectrainaccordancewiththem0lecularionpeakm/z=280inEIMS.Thetypeofcarbonsignals(5xC,3xCH,4xCH,,4xCH,)(Table2)sh0wedithadabicyclicsesquiterpeneskeletonbearingameth0xy.ahemi-… 相似文献
3.
Tong SHEN Wei Dong XIE Zhong Jian JIA 《中国化学快报》2005,16(9):1220-1222
Two new eremophilane sesquiterpenes, 15β-formic ether-6-oxo-furanoeremophilane (1) and 6α, 15β-epoxy eremophila-7(11)-en-8α, 12-olide (2) were isolation from the roots of Ligularia macrophylla. Their structures were deduced from spectroscopic methods and 2D NMR experiments. 相似文献
4.
Qiu Hong WU He Xiang WANG Kun GAO State Key Laboratory of Applied Organic Chemistry College of Chemistry Chemical Engineering Lanzhou University Lanzhou 《中国化学快报》2006,17(2)
Many Ligularia species have long been used as traditional folk medicine for theirantibiotic, antiphlogistic and antitussive activities1, and were found to be an importantsource of eremophilane. In the course of our search for bioactive sesquiterpenoids, w… 相似文献
5.
Er Wei LI Kun GAO Zhong Jian JLA 《中国化学快报》2005,16(9):1230-1232
Two new eremophilenolides, 1β-hydroxy-2β-methylsenecioyloxyeremophil-7 (11)-en- 8β (12)-olide (1), 1β-hydroxy-2β-methylsenecioyloxy-8α-methoxyeremophil-7 (11)-en-8β (12)- olide (2), were isolated from the roots of Cacalia pilgeriana. Their structures were elucidated by spectroscopic methods and X-ray diffraction analysis. 相似文献
6.
ManJunMAO ChengShanYUAN ChuanZongZOU ZhongJianJIA 《中国化学快报》2003,14(5):479-482
Two new eremophilenolides(3β-angeloyloxy-8β,10β-dihydroxy-6β-ethoxyeremophile-nolide(1)and 3β,6β-diangeloyloxy-8α-methoxy-10α-hydroxyeremophilenolide(2)were isolated from the roots of Cacalia ainsliaeflora.Their structures were elucidated by spectroscopic methods. 相似文献
7.
Jun Xi LIU Xiao Ning WEI Yan Ping SHI Run Hua LU 《中国化学快报》2005,16(12):1618-1620
Two new eremophilane sesquiterpene lactones, 1β-angeloyloxy-6β, 10β-dihydroxy-8β- methoxyeremophila-7(ll)en-8α,12-olide and 1β-angeloyloxy-6β,10α-dihydroxy-8α-methoxyeremo- phila-7( 11)en-8β, 12-olide were isolated from the extract of the whole plant of Ligularia myriocephala Ling. Their structures and stereochemistry were elucidated by various spectroscopic methods including intensive 2D-NMR techniques (COSY, gHMQC, gHMBC and ^1H-^1H NOESY) and HR-ESIMS. 相似文献
8.
A new furanoeremophilane and a new eudesmane were isolated from the roots of Ligularia veitchiana .Their structures were elucidated as 1 β,10β-epoxy-6β-isobutyryloxy-9-oxo-furanoeremophilane and 8α-hydroxy-4(15),11-eudesmadiene by spectroscopic methods. 相似文献
9.
Xue GAO Tong SHEN Wei Dong XIE Zhong Jian JIA 《中国化学快报》2006,17(3):341-343
Mainly species of Ligularia have long been used for treatment of fever, inflammation, detoxication, invigorating the circulation of blood and smoothing pain1. So far the opl- opane derivatives were not found in the genus Ligularia. Here we report the stru… 相似文献
10.
FuLinYAN AiXiaWANG ZhongJianJIA 《中国化学快报》2004,15(4):423-424
Two new benzofuran derivatives were isolated from the roots ofLigularia stenocephala.Their structures were established by spectroscopic methods and 2D NMR experiments. 相似文献
11.
From the roots of Ligularia macrophylla, a bisesquiterpene,ligumacrophyllal was isolated and its structure was elucidated on the basis of spectroscopic methods. 相似文献
12.
Two new dibenzofurans,7,8-dimethoxy-4-methyldibenzofuran-1-carboxaldehyde, named ligumedial (1) and 7,8-dimethoxy-4-methyldibenzofuran-1-carboxylic acid, named ligumediaoic acid (2), have been isolated from the underground parts of Ligularia intermedia. Their structures were elucidated by spectroscopic methods. 相似文献
13.
QuanXiangwu YanPingSHI LiYANG 《中国化学快报》2004,15(12):1441-1444
From the alcoholic extract of the whole plant of Ligularia virgaurea spp. oligocephala, three novel eremophilane sesquiterpene lactones, 6α, 10α-dihydroxy- 1-oxoeremophila-7(11), 8(9)-dien-8, 12-olide, 613, 10α-dihydroxy-1-oxoeremophila-7 (ll), 8 (9)-dien-8, 12-olide and 10α-hydroxy-1-oxoeremophila-7(l 1), 8(9)-dien-8, 12-olide were isolated. Their structures were elucidated by various spectroscopic methods including intensive 2D NMR techniques (COSY,HMQC, HMBC and ^1H-^1H NOESY) and HR-MS. 相似文献
14.
FuLinYAN AiXiaWANG ZhongJianJIA LeiHE 《中国化学快报》2003,14(12):1253-1254
A new isopropenyl benzofuran-type tetramer was isolated from the roots of ligularia stenocephala and its structure was established by spectroscopic methods. 相似文献
15.
Qiu Hong WU He Xiang WANG Kun GAO 《中国化学快报》2006,17(2):215-217
Two new eremophilenolides were isolated from the roots of Ligularia muliensis. Their structures were elucidated on the basis of the spectroscopic analysis as 6β-acetoxy-8β-hydroxyleremophil-7(11)-en- 12,8α-olide 1 and 6α-hydroxy-8βH-eremophil-7(11)-en- 12,Sa-olide 2. 相似文献
16.
ErWeiLI KunGAO ZhongJianJIA 《中国化学快报》2004,15(2):194-196
A new stigmasterol 3β, 7α, 22-trihydoxystigmast-5-ene (1) and a new eremophilenolide 8α-methoxy-6β-angeloyloxyeremophil-7(1 l)-en-8β, 12-olide-14-oic acid (2) were isolated from Ligularia dolichobotrys Diels. Their structures were deduced on the basis of spectral data. 相似文献
17.
18.
Two new pyrrolizidines named lankongensisine A (1), B (2) were isolated from the roots of Ligularia lankongensis collected in Lijiang, Yunnan, and their structures were established by spectroscopic analysis. 相似文献
19.
Ai‐Min Tan Hong‐Ping He Mian Zhang Zheng‐Tao Wang Xiao‐Jiang Hao 《Helvetica chimica acta》2007,90(1):101-104
In continuation of a systematic investigation into the chemotaxonomic and bioactive components of pyrrolizidine alkaloids and sesquiterpenoids of Ligularia plants, two new, highly oxygenated, rare bisabolene sesquiterpenes, compounds 1 and 2 , were isolated from the roots of Ligularia lankongensis. Their structures and relative configurations were elucidated by means of 1D‐ and 2D‐NMR as well as MS analyses. 相似文献
20.
Four new benzofuran derivatives were isolated from the roots of Ligularia stenocephala; they were named as ligustenin A ( 1 ), B ( 2 ), C ( 3 ) and D ( 4 ), and the structures were established by spectroscopic methods including 2D NMR techniques. Ligustenin A (1) was found to exhibit potent anti‐tumor activity against HL‐60 (human leukemia cells), Bel‐7402 (human hepatoma cells) and HO‐8910 (human ovarian neoplasm cells) with IC50 values of 18.6, 27.6 and 57.5 μM, respectively. 相似文献