Reaction of 3,4-dioxohexane-1,6-dioic acid esters with 2,4-dinitrophenylhydrazine

Reaction was studied of 3,4-dihydroxyhexa-2,4-diene-1,6-dioic acid esters with 2,4-dinitrophenylhydrazine that led to the formation of esters of (3E)-3-[2-(2,4-dinitrophenyl)-hydrazinylidene]-4-oxohexane-1,6-dioic and (3E,4E)-3,4-bis[2-(2,4-dinitrophenyl)hydrazinylidene]-hexane-1,6-dioic acids. The structural features of compounds synthesized were established from the data of IR and NMR spectra and X-ray diffraction (XRD) analysis.     

Reaction of dibenzylphosphinous acid with formic acid esters

Summary The reaction of dibenzylphosphinous acid with formic acid esters was studied in the presence of sodium. Here we obtained dibenzylmethylolphosphine oxide and the enol form of the phenylalkoxybenzylphosphorylacetaldehyde.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1085–1088, June, 1965     

Reaction of oxochloroalkenes with phosphorous acid esters

Conclusions 2-Qxo-3-methyl-5-chloro-3-hexene and trans-2-oxo-5-chloro-3-heptene, adequate low-molecular-weight models of labile carbonylallyl groups in poly(vinyl chloride) macromolecules, were synthesized. Tributyl phosphite reacts with the model compounds at the oxovinylene fragment via a step of formation of intermediate phosphorane structures, which are converted to stable ketophosphonates during heating.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 1106–1108, May, 1985.     

Reaction of arynes with amino acid esters

An efficient route to a variety of 2-phenylindolin-3-ones from amino acid methyl esters has been developed. The reaction of amino acid methyl esters with benzyne prepared from 2-(trimethylsilyl)phenyl triflate and CsF gave 2-phenylindolin-3-ones in moderate to good yields.     

Colorimetric monitoring of solid-phase aldehydes using 2,4-dinitrophenylhydrazine

A simple and rapid method to achieve colorimetric monitoring of resin-bound aldehydes, based on ambient temperature reaction with 2,4-dinitrophenylhydrazine (DNPH) in the presence of dilute acid, has been developed as an adjunct to solid-phase organic synthesis and combinatorial chemistry. By this test, the presence of aldehydes is indicated by a red to dark-orange appearance, within a minute. Alternatively, resins that are free of aldehydes or in which aldehyde functions have reacted completely retain their original color. The DNPH test was demonstrated for poly(ethylene glycol)-polystyrene (PEG-PS), aminomethyl polystyrene (AMP), cross-linked ethoxylate acrylate resin (CLEAR), and acryloylated O,O'-bis(2-aminopropyl)poly(ethylene glycol) (PEGA) supports and gave results visible to the naked eye at levels as low as 18 micromol of aldehyde per gram of resin.     

Reaction products of selenophosphorus acid esters with sulfuryl chloride

Conclusions Selenophosphorus acid esters react with SO₂Cl₂ to form -chlorose lenophosphonium salts, while reaction of O,O-dialkyl selenophosphoric acids with SO₂Cl₂ under analogous conditions gives O,O-dialkyl Se-chloro selenophosphates.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khi miche ska ya, No. 1, pp. 153–156, January, 1977.     

Reaction of 5-phenylpenta-2,4-dienoic acid with benzene in trifluoromethanesulfonic acid

The reaction of 5-phenylpenta-2,4-dienoic acid with benzene in CF₃SO₃H, depending on the reaction conditions, gives three products, namely, 5,5-diphenylpent-2-enoic acid and tetralone and indanone derivatives. These carbocyclic compounds are formed through the addition of two benzene molecules to the starting diene acid and subsequent intramolecular acylation.

     

Reactions of 3,4-dihydroxyhexa-2,4-diene-1,6-dioic acid esters with anthranilic acid hydrazide

Reactions of 3,4-dihydroxyhexa-2,4-diene-1,6-dioic acid esters with anthranilic acid hydrazide lead to the formation of 3,4-bis(2-aminobenzoylhydrazono)hexane-1,6-dioic acid esters. Structural features of the synthesized compounds are discussed.