A report on the 31st Symposium on Heteroatom Chemistry of the Chemical Society of Japan

The 31st domestic Chemical Society of Japan Symposium on Heteroatom Chemistry was held in Wakayama during the period of December 8–10, 2004, under the management of Waro Nakanishi and Satoko Hayashi of Wakayama University. About 250 chemists from various academic institutes and industries enjoyed five plenary lectures, 40 oral presentations, and 72 poster presentations. © 2005 Wiley Periodicals, Inc. Heteroatom Chem 16:535–547, 2005; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20134     

Report on the 28th symposium on heteroatom chemistry of the chemical society of Japan

The 28th domestic Symposium on Heteroatom Chemistry of the Chemical Society of Japan was held at Saitama Culture Center in Saitama during the period of December 12–14, and about 250 chemists from various academic institutes and industries took part in the symposium. There were four plenary lectures, 44 oral presentations, and 52 poster presentations. The present article describes abstracts of the plenary lectures and graphical abstracts of oral presentations. Titles of poster presentations are also given. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:1–12, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10073     

A report on the 29th symposium on heteroatom chemistry of the chemical society of Japan

The 29th domestic Chemical Society of Japan Symposium on Heteroatom Chemistry was held in Hiroshima during the period of December 12–14, 2002, under the management of Tetsuo Otsubo of Hiroshima University. About 250 chemists from various academic institutes and industries enjoyed four plenary lectures, 44 oral presentations, and 53 poster presentations. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:387–398, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10186     

A report on the “new frontiers in group 13 chemistry” symposium from the 88th Canadian Society for Chemistry Conference and Exhibition

The 88th Canadian Society for Chemistry Conference and Exhibition was held in Saskatoon, Saskatchewan, during the period of May 28–June 1, 2005. More than 250 chemists from various academic institutes and industries enjoyed five plenary lectures, thirteen oral presentations and a plethora of poster presentations. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:323–332, 2007; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20287     

Catechol–bisphosphonate conjugates: New types of chelators for metal intoxication therapy

Three new types of bisphosphonates conjugated with catechol were synthesized to explore their possibilities for the treatment of metal intoxication. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:549–555, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20056     

A new approach to synthesis of 3,3‐dialkyl‐3,4‐dihydroisoquinoline derivatives

The synthesis of 3,3‐dialkyl‐3,4‐dihydroisoquinolines via heterocyclization in three‐component reaction of an activated arene with isobutyraldehyde and nitriles is described. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:486–493, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20049     

13C and 31P high resolution solid state NMR studies of cyclophosphamide and its analogues

Three anticancer agents cyclophosphamide, iphosphamide, and bromophosphamide were studied using ¹³C and ³¹P SS NMR. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:388–394, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20028     

A novel reduction of sodium alkyl thiosulfates with InCl3(cat.)/Sm(0) system in aqueous media: Facile synthesis of disulfides

A novel reduction of sodium alkyl thiosulfates with InCl₃(cat.)/Sm(0) system in aqueous media has been developed, which generates the corresponding disulfides in good yields. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:376–379, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20023     

Synthesis of new potential chelating agents: Catechol–bisphosphonate conjugates for metal intoxication therapy

In a quest for better chelating therapy drugs for the treatment of intoxication by Fe, Al, or actinides, three new series of bisphosphonates conjugated with catechol were synthesized. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:251–257, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20013     

New route to O,O‐diethyl phosphorocyanidate

A new and efficient route for synthesis of diethyl phosphorocyanidate 7a by decomposition of diethyl phosphoryl‐1,2,4,‐dithiazolin‐5‐one is described. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:395–397, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20027     

The semiempirical study on the addition of the chiral ammonium hypophosphite to an aldehyde

The PM3 and AM1 semiempirical computations were performed in order to explain the stereochemistry of the addition of the chiral α-methylbenzylammonium hypophosphite to an aldehyde, which is stereoselective to 100%. Both mechanisms: one considering the intermediate formation of α-hydroxy phosphonous acids followed by the nucleophilic substitution with a chiral amine and the second considering the formation of a Schiff base followed by the addition of hypophosphorous acid to an azomethine bond were taken. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:162–168, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10230     

Michael adducts‐synthons for pyrazolidinediones,isoxazolidinediones, pyrimidinetriones,and thioxopyrimidinediones

4‐Substituted pyrazolidinediones, isoxazolidinediones, and 5‐substituted pyrimidinetriones, thioxopyrimidinediones were obtained by exploiting gem‐diester functionality in mono‐ and di‐substituted dimethyl malonates. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:477–481, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20053     

A facile and efficient synthesis of bisazine derivatives

1,4‐Phenylenediamine was condensed with acetylacetone to give 4,4′‐[1,4‐phenylenedi‐(nitrilo)]‐dipenten‐2‐ol 1 . Compound 1 reacted with different organic reagent to give bisazine derivatives. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:293–299, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20017     

The reaction of organozinc reagents with trifluoroacylated phosphonates: Synthesis of trifluoromethylated α, β‐unsaturated esters with an active methylene moiety

The consecutive reaction of phosphonates 1 with n‐butyllithium, trifluoroacetic anhydride, and organozinc compounds gives trifluoromethylated α,β‐unsaturated esters with an active methylene moiety and predominant Z‐selectivity in 54–78% (3 steps) yields. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:289–292, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20018     

An iterative strategy for the synthesis of oligothiophenes by catalytic cross-coupling reactions

An iterative strategy for the synthesis of new sulfur-functionalized oligothiophenes by Suzuki or Stille cross-coupling reactions was applied to the reaction of 4-bromo-tert-butylphenylthioether with thiophene derivatives. The planarity of the oligothiophenes obtained was confirmed by the single-crystal X-ray structure analysis of 2-(4′-tert-butylthiophenyl)thiophene, which shows a potentially large electronic conjugation length. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:121–126, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10224     

Iodochlorination of silyl- and germylphenylacetylenes

Reactions of Si- and Ge-substituted alkynes with KICl₂ were investigated. (1-Germatranyl)-phenylacetylenes and (triphenylsilyl)phenylacetylene gave Z-iodochloroalkenes with chlorine and phenyl groups attached to the same carbon atom. Adduct structures were confirmed by X-ray diffraction studies. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:169–174, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20001     

Reaction of chlorides of phosphoric,sulfonic, and carboxylic acids on solid potassium carbonate surface under PTC circumstances

Simple syntheses of phosphoric ( 4 ) and carboxylic ( 6 ) acid anhydrides have been elaborated by means of solid potassium carbonate in phase‐transfer catalytic acylation. Behavior of various acid chlorides, phosphoric ( 1 ), sulfonic ( 2 ), and carboxylic ( 8 ), have also been studied toward potassium carbonate in the presence of lipophilic quaternary ammonium salt. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:447–450, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20039     

Novel conversion of 6H-1,3,5-oxathiazine S-oxides into 5-membered heterocyclic compounds

5H-1,2,4-oxathiazoles were efficiently synthesized from 6H-1,3,5-oxathiazine S-oxides by thermal cycloreversion of the substrates and the products were effectively converted into 1,2,4-thiadiazoles. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:175–186, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20004     

Calix[4]arene phosphonates - recognition of amino alcohols in water

The water-soluble calix[4]arenes based cavitands were obtained in good yield by introduction of phosphonic acids groups at the upper rim; we describe the design, synthesis, and formation of the complexes with ephedrine, norephedrine, and noradrenaline hydrochloride in the phosphate buffer at pD 7.3. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:155–161, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10229     

Phenylbiguanide as electron donor in heterocyclic synthesis

Phenylbiguanide reacts with some π-acceptors such as TCNE, TCNQ, CNIND, DCNQ, and CHL-o, if any. opy; 2003 Wiley Periodicals, Inc. Heteroatom Chem 15:63–66, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10213