Using N‐Tosylhydrazone as a Double Nucleophile in the Palladium‐Catalyzed Cross‐Coupling Reaction To Synthesize Allylic Sulfones |
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| Authors: | Ping‐Xin Zhou Dr. Yu‐Ying Ye Dr. Lian‐Biao Zhao Dr. Jian‐Ye Hou Xing Kang Dao‐Qian Chen Qian Tang Jie‐Yu Zhang Qi‐Xing Huang Lan Zheng Jun‐Wei Ma Prof. Peng‐Fei Xu Prof. Yong‐Min Liang |
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| Affiliation: | 1. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 (P.R. China), Fax: (+86)?931‐8912582;2. College of Chemical Engineering, Northwest University for Nationalities, Lanzhou (P.R. China);3. Xinyang College of Agriculture and Forestry, Xinyang (P.R. China) |
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| Abstract: | Without extra addition of sulfinate salt, allylic sulfones were synthesized by palladium‐catalyzed cross‐coupling of aryl iodide with N‐tosylhydrazone. In this transformation, not only the diazo compound but also the sulfinate salt, which were both generated in situ from base‐mediated decomposition of the N‐tosylhydrazone, was used as nucleophilic partner. |
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| Keywords: | atom economy carbenes double nucleophiles palladium tosylhydrazone |
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