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Facile synthesis,characterisation and anti‐inflammatory activities of ferrocenyl ester derivatives of 4‐arylidene‐5‐imidazolinones
Authors:Dilip N. Shinde  Rajiv Trivedi  N. Vamsi Krishna  L. Giribabu  B. Sridhar  B.B. Rathod  R.S. Prakasham
Affiliation:1. Inorganic and Physical Chemistry Division, CSIR‐Indian Institute of Chemical Technology, Hyderabad, India;2. Academy of Scientific and Innovative Research (AcSIR), CSIR‐IICT Campus, Hyderabad, India;3. Center for X‐ray Crystallography, CSIR‐Indian Institute of Chemical Technology, Hyderabad, India;4. Medicinal Chemistry and Biotechnology Division, CSIR‐Indian Institute of Chemical Technology, Hyderabad, India
Abstract:This article describes the synthesis, optoelectronic properties and anti‐inflammatory activities of a series of seven ferrocenyl ester‐linked 4‐arylidene‐5‐imidazolinone conjugates. Three different types of ortho‐, meta‐ and para‐substituted ferrocenyl esters have been prepared. Their UV–Vis spectra and electrochemical studies are described. The structure of one of the conjugates was confirmed by single‐crystal X‐ray diffraction study. These conjugates exhibited moderate anti‐inflammatory activities.
Keywords:anti‐inflammatory  arylidene  ferrocene  imidazolinones
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