A Reconfigurable DNA Accordion Rack |
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| Authors: | Yeongjae Choi Hansol Choi Amos C. Lee Hyunung Lee Prof. Sunghoon Kwon |
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| Affiliation: | 1. Department of Electrical and Computer Engineering, Seoul National University, Gwanak-gu, Seoul, Republic of Korea;2. Interdisciplinary Program for Bioengineering, Seoul National University, Gwanak-gu, Seoul, Republic of Korea;3. Institute of Entrepreneurial Bio Convergence, Seoul National University, Gwanak-gu, Seoul, Republic of Korea;4. Seoul National University Hospital Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea |
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| Abstract: | DNA nanostructure‐based mechanical systems that control the distance between elements of interest have demonstrated great potential for various applications, including nanoplasmonic systems, molecular reactors, and other nanotechnology platforms. However, previously reported systems could not collectively manipulate a 2D or 3D nanoscale network of elements to various forms in multiple stages. A reconfigurable DNA accordion rack structure is introduced that is a DNA beam lattice that changes its conformation with a small amount of short‐length DNA locks as the controlling input. The lattice shape of the 2D DNA accordion rack and the diameter and the height of the 3D DNA nanotubular structure made of the DNA accordion rack could be controlled. Furthermore, by sequentially repeating the detachment and the attachment of the different DNA locks using strand displacement, the shape reconfiguration was repeatedly carried out. |
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| Keywords: | DNA nanomachines DNA nanotechnology DNA structures nanopores self-assembly |
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