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Label‐Free Biosensing over a Wide Concentration Range with Photonic Force Microscopy |
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| Authors: | Seungjin Heo Prof. Kipom Kim Prof. Yong‐Hoon Cho |
| Affiliation: | 1. Graduate School of Nanoscience & Technology (WCU), Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305‐701 (Republic of Korea);2. Department of Physics, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305‐701 (Republic of Korea);3. Graphene Research Center, KAIST Institute for the NanoCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305‐701 (Republic of Korea) |
| Abstract: | We present a label‐free biosensor that measures molecular interactions between biomolecules on the surface of a probe bead and substrate over a wide concentration range. This system is capable of detecting target biomolecules with concentrations varying from 10 nM to 0.1 pM , with high selectivity and sensitivity. |
| Keywords: | biosensors optical tweezers photonic force microscopy scanning force microscopy single‐molecule studies |