| Improved Synthesis and Resolution of α-N-Benzoyl-β(3-Qumolyl)-DL-α-Alanine Methyl Ester |
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| 摘 要： | ![]()
The title compound has been synthesized and resolved previously by T. M. Kubiak. In our searching of new potent agonists of LH-RH(luteinizing hormone releasing hormone), α-N-t-butyloxycarbonyl-β-3-quinolyl)-D-α-alanine and its L-isomer were synthesized. The unprotected.optically active amino acids were obtained by enzymatic hydrolysis of the title compounds, followed by hydrolysis in 6 mol/L hydrochloric acid. The title compound was synthesized initially with 3-quinolinecar-
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| 收稿时间： | 1990-10-20 |
Improved Synthesis and Resolution of α-N-Benzoyl-β(3-Qumolyl)-DL-α-Alanine Methyl Ester |
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| Zhang Yawen,Shen Zongxuan. Improved Synthesis and Resolution of α-N-Benzoyl-β(3-Qumolyl)-DL-α-Alanine Methyl Ester[J]. Chemical Research in Chinese University, 1991, 7(4): 261-265 |
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| Authors: | Zhang Yawen Shen Zongxuan |
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| Affiliation: | Department of Chemistry, Suzhou University, Suzhou |
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| Abstract: | ![]()
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| Keywords: | Improved synthesis Resolution Amino acid |
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