Effect of Laser Field and Mechanical Force on Deoxyribonucleic Acid Melting |
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| Authors: | PAN Bing-Yi ZHANG Ling-Yun DOU Shuo-Xing WANG Peng-Ye |
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| Affiliation: | Key Laboratory of Soft Matter Physics, Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190 |
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| Abstract: | We propose a physics method to study the effect of laser field and mechanical force on the melting process of double-stranded deoxyribonucleic acid (DNA). A two-dimensional lattice model is established for DNA molecules stuck on the surface, and the stretching energy of the hydrogen bond and stacking energy for each DNA molecule are calculated by using a nonlinear potential. A real-time algorithm is employed to deal with the dynamics process of DNA melting. Numerical results explain the experimental observations. The spatial distribution of the laser field determines the sequences of DNA melting. The simulation has shown the dependence of the final number of melted DNA on the laser field and mechanical force. |
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| Keywords: | 87.10.-e 87.15.-v 87.64.kv |
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