Pig Liver Esterase-catalyzed Hydrolysis of Three Diesters of meso-Bicyclic Dicarboxylic Acid and Three Tetraesters of Tetrahydrofuran-2, 3,4,5-tetracarboxylic Acid |
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Authors: | MA Guang-En Tamm Ch |
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Affiliation: | 1. National Institutes of Pharmaceutical Research & Development, Beijing 102206, P. R. China; 2. Institut fur Organishe Chemie der Universitat Basel, CH-4056 Basel Switzerland |
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Abstract: | Three diesters of exo- syn-meso-oxabicyclo (2, 2, 1 ) -hept- 5- ene- 2, 3- dicarboxylic acid and three tetraesters of tetrahydrofuran-2, 3, 4, 5-tetracarboxylic acid were synthesized and tested with enantioselective hydrolysis catalyzed by pig liver esterase(PLE). The results of the PLEcatalyzed hydrolysis were discussed. |
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Keywords: | Oxabicyclo(2 2 1 )-hept-5-ene-2 3-dicarboxylic acid Tetrahydrofuran-2 3 4 5- tetracarboxylic acid Esterification Hydrolysis Pig liver esterase(PLE) |
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