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Activation of a Photodissociative Ruthenium Complex by Triplet–Triplet Annihilation Upconversion in Liposomes
Authors:Sven H. C. Askes  Azadeh Bahreman  Dr. Sylvestre Bonnet
Affiliation:Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden (The Netherlands)
Abstract:Liposomes capable of generating photons of blue light in situ by triplet–triplet annihilation upconversion of either green or red light, were prepared. The red‐to‐blue upconverting liposomes were capable of triggering the photodissociation of ruthenium polypyridyl complexes from PEGylated liposomes using a clinical grade photodynamic therapy laser source (630 nm).
Keywords:chemotherapy  liposomes  photochemistry  prodrug  ruthenium
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