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月季花抗氧化活性成分研究
引用本文:王蕾,符玲,敬林林,阿有梅,贾陆. 月季花抗氧化活性成分研究[J]. 高等学校化学学报, 2012, 33(11): 2457-2461. DOI: 10.7503/cjcu20120335
作者姓名:王蕾  符玲  敬林林  阿有梅  贾陆
作者单位:1.郑州大学药学院,郑州,450001;2.郑州大学药学院,郑州,450001;3.郑州大学药学院,郑州,450001;4.郑州大学药学院,郑州,450001;5.郑州大学药学院,郑州,450001
摘    要:以活性追踪为指导分离和纯化了月季花中具有1,1-二苯基-2-三硝基苯肼(DPPH)自由基清除活性的成分.从月季花中分离得到了10个黄酮类化合物,采用光谱法对其结构进行了表征,并对它们的自由基清除活性进行了评价.结果表明,化合物1为新化合物,化合物1,2,4和9具有较强的清除DPPH自由基的活性.

关 键 词:月季  化学成分  槲皮素3-O-(2  6-二没食子酰基)-β-D-葡萄糖苷  
收稿时间:2012-04-10

Studies of Chemical Constituents from Rosa chinensis Jacq.
WANG Lei,FU Ling,JING Lin-Lin,A You-Mei,JIA Lu. Studies of Chemical Constituents from Rosa chinensis Jacq.[J]. Chemical Research In Chinese Universities, 2012, 33(11): 2457-2461. DOI: 10.7503/cjcu20120335
Authors:WANG Lei  FU Ling  JING Lin-Lin  A You-Mei  JIA Lu
Affiliation:School of Pharmacy, Zhengzhou University, Zhengzhou 450001, China
Abstract:In order to separate and purify the chemical constituents from Rosa chinensis Jacq., which have DPPH· scavenging capacity, dried Rosa chinensis flowers were extracted three times with 95% ethanol under reflux. This extract was then fractionated by column chromatography over silica gel, MCI gel, Sephadex LH-20, etc. A new compound[quercetin 3-O-(2,6-digalloyl)-β-D-glucoside, 1] and nine known compounds (2-10) were isolated from Rosa chinensis Jacq. and identified using spectroscopic methods. Their antioxidant activity was assayed using DPPH· experiments. The results indicated that compounds 1, 2, 4 and 9 had good antioxidant activity.
Keywords:Rosa chinensis Jacq.') href=#>Rosa chinensis Jacq.  Chemical constituent  O-(2″,6″-digalloyl)-β-D-glucoside') href=#>Quercetin 3-O-(2″,6″-digalloyl)-β-D-glucoside
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