Synthesis and Characterization of Benzochromeno[2,3‐b]tetrahydroquinolinone Derivatives |
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| Authors: | Guang‐Fan Han Ming Wang Yan Jin Li‐Zhuang Chen |
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| Affiliation: | Biological and Chemical Engineering Institute, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China |
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| Abstract: | We report on a novel method for the preparation of a new series of benzochromeno[2,3‐b]tetrahydroquinolin‐1‐one derivatives. The title compounds are prepared by the 5‐substituted‐1,3 ‐cyclohexanedione and 3‐amino‐1‐aryl‐1H‐benzo[f]chromene‐2‐carbonitrile or 2‐amino‐4‐aryl‐4H‐benzo[h]chromene‐3‐carbonitrile using dilute HCl, K2CO3, and Cu2Cl2 as catalysts. The method has the advantages of simple operation, high efficiency, and low toxicity. The structures of all compounds are characterized by elemental analysis, IR, MS, and 1H NMR spectra. Two single crystals are characterized by using X‐ray diffraction. |
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