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A New Approach for the Synthesis of Highly Substituted Aromatic Rings: The Alkyne‐Mediated Approach |
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| Authors: | Prof. Philip J. Parsons Daniel R. Jones Alex C. Padgham Lewis A. T. Allen Dr. Clive S. Penkett Robert A. Green Dr. Andrew J. P. White |
| Affiliation: | 1. Department of Chemistry, Imperial College London, South Kensington, London, UK;2. School of Chemistry, University of Southampton, Southampton, UK |
| Abstract: | Pentasubstituted aromatic rings serve as templates for drug design and can be conveniently prepared by the thermolysis of suitably substituted alkynes under microwave conditions. |
| Keywords: | alkynes aromatic rings cyclization furan microwave chemistry thermolysis |