Partially Oxidized Graphene/Metallic Single‐Walled Carbon Nanotubes Film‐Coated Electrode for Nanomolar Detection of Dopamine |
| |
| Authors: | Ashok K. Sundramoorthy Sundaram Gunasekaran |
| |
| Affiliation: | Department of Biological Systems Engineering, University of Wisconsin‐Madison, 460 Henry Mall, Madison, WI 53706, USA |
| |
| Abstract: | Enriched metallic single‐walled carbon nanotubes (mSWCNTs) were dispersed in aqueous solution of partially oxidized graphene (po‐Gr). As‐prepared po‐Gr/mSWCNTs suspension was used to modify glassy carbon electrode (GCE) surface, which showed high electrocatalytic activity for dopamine (DA) oxidation in pH 7.0 phosphate buffered saline (PBS) solution. Using po‐Gr/mSWCNTs/GCE we could detect DA from 350 to 3600 nM, with a detection limit down to 25 nM in physiological condition (in pH 7.0 PBS); whereas, po‐Gr/GCE (without mSWCNTs) and bare GCE produced measurable signals only at or above 200 nM DA. Thus, the po‐Gr/mSWCNTs film we fabricated is a promising nanomaterial for fabrication of biosensors for nanomolar detection of DA. |
| |
| Keywords: | Metallic single‐walled carbon nanotubes Oxidized graphene Dopamine detection Electrocatalyst Biosensors |
|
|
