Aerobic Asymmetric Dehydrogenative Cross‐Coupling between Two CH Groups Catalyzed by a Chiral‐at‐Metal Rhodium Complex |
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| Authors: | Yuqi Tan Wei Yuan Dr. Lei Gong Prof. Dr. Eric Meggers |
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| Affiliation: | 1. Key Laboratory for Chemical Biology of Fujian Province and Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005 (P.R. China);2. Fachbereich Chemie, Philipps‐Universit?t Marburg, Hans‐Meerwein‐Stra?e 4, 35043 Marburg (Germany) |
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| Abstract: | A sustainable C? C bond formation is merged with the catalytic asymmetric generation of one or two stereocenters. The introduced catalytic asymmetric cross‐coupling of two C ? H groups with molecular oxygen as the oxidant profits from the oxidative robustness of a chiral‐at‐metal rhodium(III) catalyst and exploits an autoxidation mechanism or visible‐light photosensitized oxidation. In the latter case, the catalyst serves a dual function, namely as a chiral Lewis acid for catalyzing enantioselective enolate chemistry and at the same time as a visible‐light‐driven photoredox catalyst. |
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| Keywords: | asymmetric catalysis C H activation green chemistry oxygen rhodium |
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