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Pd‐Catalyzed Carboamination of Alkylidenecyclopropanes: Synthesis of Congested Pyrrolidines and Piperidines |
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| Authors: | Phillip R. Lazzara Keegan P. Fitzpatrick Dr. Chad C. Eichman |
| Affiliation: | Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL, USA |
| Abstract: | The synthesis of densely functionalized N‐heterocycles is an ongoing challenge in chemical synthesis. Herein, we report an efficient method for the construction of pyrrolidine and piperidine scaffolds using a palladium‐catalyzed carboamination of alkylidenecyclopropanes. |
| Keywords: | aminoarylation carboamination homogeneous catalysis nitrogen heterocycles palladium catalysis |