Novel approaches for the preparation of magnetic nanogels via covalent bonding |
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| Authors: | Aintzane Pikabea Jacqueline Forcada |
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| Affiliation: | Bionanoparticles Group, Department of Applied Chemistry, UFI 11/56, Faculty of Chemistry, University of the Basque Country UPV/EHU, Apdo. 1072, Donostia‐San Sebastián, Spain |
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| Abstract: | Here, novel methods to encapsulate magnetic nanoparticles (MNPs) into dual‐stimuli‐responsive nanogels via covalent bonding are reported. With the aim of strengthening the attachment of MNPs with the nanogels, primary amine‐ and epoxide‐functionalized stimuli‐sensitive poly(2‐(diethylamino)ethyl methacrylate) (PDEAEMA)‐based nanogels were firstly synthesized. Then, MNPs were incorporated into the nanogels by using different methods, obtaining different families of magnetic nanogels (MNGs). Those MNGs, showing pH‐sensitivity and high superparamagnetic response, could be considered to be widely useful as theranostic agents in biomedical applications. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017 , 55, 3573–3586 |
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| Keywords: | covalent bonding dual‐sensitivity functionalization of nanogels magnetic response magneto‐nanogels |
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