Plasmon nanoruler for monitoring of transient interactions |
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| Authors: | K. V. Baryshnikova M. I. Petrov T. A. Vartanyan |
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| Affiliation: | 1. ITMO University, St. Petersburg, Russia;2. Phone: +7 921 978 1131;3. St. Petersburg Academic University, St. Petersburg, Russia |
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| Abstract: | Nanoplasmonics has been rapidly developing for the last 30 years and it finds applications in many areas, including medicine, biology, and chemistry. Plasmon nanoparticles are used in biosensing and genomics, for bioimaging of cell structures, for targeted delivery of drugs and photothermolysis of cancer cells. All these applications often require real‐time detection of nanoparticle position at the nanoscale making this problem highly relevant. We propose new far‐field method of real‐time detection of plasmon particles location by detecting the magnitude of localized surface plasmon resonance splitting. In contrast to the existing methods based on the shift of plasmon resonance central line, the suggested technique is sensitive to the surface, and allows detecting metal nanoparticle position relatively to internal interfaces such as cell walls or chemical phase boundaries. The presented numerical simulations are aimed on modelling of biological tissues environment and demonstrate the possibility of high accuracy detection of nanoparticle position. (© 2015 WILEY‐VCH Verlag GmbH &Co. KGaA, Weinheim) |
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| Keywords: | silver nanoparticles plasmons nanorulers |
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