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Silver‐Catalyzed 7‐exo‐dig Cyclization of Silylenolether‐ynesulfonamides |
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| Authors: | Dr. Clément F. Heinrich Indira Fabre Dr. Laurence Miesch |
| Affiliation: | 1. Laboratoire de Chimie Organique Synthétique, Institut de Chimie, Strasbourg, France;2. Département de Chimie, Ecole Normale Supérieure—PSL Research University, Sorbonne Universités—UPMC Univ Paris 06, CNRS UMR 8640 PASTEUR, Paris, France |
| Abstract: | Cyclization of silylenolether‐ynesulfonamides proceeds at ambient temperature under mild reaction conditions under silver catalysis. Bridged compounds were obtained exclusively through 7‐exo‐dig reactions. The protocol is applicable to a wide range of substrates, thus leading to azabicyclic frameworks. |
| Keywords: | cyclizations heterocycles silver structure elucidation synthetic methods |