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Chain Walking of Allylrhodium Species Towards Esters During Rhodium‐Catalyzed Nucleophilic Allylations of Imines |
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| Authors: | Dr. Jose I. Martínez Joshua J. Smith Dr. Hamish B. Hepburn Prof. Hon Wai Lam |
| Affiliation: | 1. School of Chemistry, University of Nottingham, Nottingham, UK;2. http://www.nottingham.ac.uk/～pczhl/ |
| Abstract: | Allylrhodium species derived from δ‐trifluoroboryl β,γ‐unsaturated esters undergo chain walking towards the ester moiety. The resulting allylrhodium species react with imines to give products containing two new stereocenters and a Z‐alkene. By using a chiral diene ligand, products can be obtained with high enantioselectivities, where a pronounced matched/mismatched effect with the chirality of the allyltrifluoroborate is evident. |
| Keywords: | allyltrifluoroborates asymmetric catalysis imines isomerization rhodium |