First Diastereoselective PasseriniSmiles and UgiSmiles Reactions Using Chiral Aldehydes |
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| Authors: | Palakodety Radha Krishna Gandrath Dayaker D. Venkata Ramana Ramesh Kunde |
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| Affiliation: | 1. D‐211, Discovery Laboratory, Organic and Biomolecular Chemistry Division, CSIR‐Indian Institute of Chemical Technology, Hyderabad‐500007, India, (phone: +91‐40‐27193158;2. fax: +91‐40‐27160387) |
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| Abstract: | A diastereoselective O/N‐arylative Passerini/Ugi reaction of chiral aldehydes with commercially available isocyanides affording O‐aryl amides and N‐aryl amides, respectively, as products in moderate to good yields, together with de values, is reported. |
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| Keywords: | Passerini Smiles reaction Ugi Smiles reaction Isonitriles Diversity‐oriented synthesis Multicomponent reactions |
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