| 对羟基苯甲酸、水杨酸分子印迹聚合物分子识别性质的 研究 |
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| 引用本文： | 张铁莉,刘锋,王俊,李克安. 对羟基苯甲酸、水杨酸分子印迹聚合物分子识别性质的 研究[J]. 化学学报, 2001, 59(10): 1623-1627 |
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| 作者姓名： | 张铁莉 刘锋 王俊 李克安 |
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| 作者单位： | 北京大学化学与分子工程学院 |
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| 摘 要： | 以对羟基苯甲酸(4-HBA)为模板分子，4-乙烯吡啶(4-Vpy)为功能单体，制备得到了4-HBA分子印迹聚合物P(4-HBA)，研究了该聚合物的分子识别机理，并与在同样条件下制备的水杨酸(SA)分子印迹聚合物P(SA)进行了分子识别能力的比较。结果表明：P(SA)比P(4-HBA)具有更好的分子识别能力。这是由于SA的酸性较4-HBA强，因此与碱性功能单体4-Vpy之间的静电作用更强，从而得到的复合物更稳定。本实验结果证明：功能单体与模板分子形成稳定的复合物是得到分子识别能力高的模板聚合物的前提条件。本文将有助于对分子印迹的过程以及分子印迹聚合物分子识别机理的进一步理解，并且对于根据模板分子的性质预测MIP的分子识别能力也将具有一定的指导意义。
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| 关 键 词： | 对羟基苯甲酸 水杨酸P 分子印迹聚合物 模板分子 吡啶P 分子识别 |
| 修稿时间： | 2001-06-28 |
Study on the molecular recognition properties of 4-hydroxybenzoic acid-imprinted polymer and salicylic acid-imprinted polymer |
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| Zhang Tieli,Liu Feng,Wang Jun,Li Kean. Study on the molecular recognition properties of 4-hydroxybenzoic acid-imprinted polymer and salicylic acid-imprinted polymer[J]. Acta Chimica Sinica, 2001, 59(10): 1623-1627 |
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| Authors: | Zhang Tieli Liu Feng Wang Jun Li Kean |
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| Abstract: | A molecularly imprinted polymer (MIP) for 4-hydroxybenzoic acid [P(4- HBA)] was prepared using 4-vinylpyridine (4-Vpy) as a functional monomer. Its molecular recognition mechanism was studied. And a comparison was made to evaluate its molecular recognition ability with that of salicylic acid-imprinted polymer [P(SA)]. The result shows that the molecular recognition ability of P(SA) is higher than that of P(4-HBA). The reason is that SA is stronger than 4-HBA in acidity and SA can form a more stable complex with 4-Vpy. which makes P(SA) have a higher molecular recognition ability. This study confirms that is is a prerequisite that the template should form a stable complex with the functional monomer in the preparation of MIP in order to obtain a MIP with high molecular recognition ability. Furthermore, this study will be helpful for us to understant the mechanism of molecular imprinting and molecular recognition of MIPs. Also, it will be of instructive significance for us to predict the selectivity of MIPs according to the properties of templates. |
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| Keywords: | P-HYDROXYL BENZOIC ACID SALICYLIC ACID P PYRIDINE P OLECULAR RECOGNITION |
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