A Practical and General Base‐Catalyzed Carbonylation of Amines for the Synthesis of N‐Formamides |
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| Authors: | Dr. Wanfang Li Prof. Dr. Xiao‐Feng Wu |
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| Affiliation: | Leibniz‐Institut für Katalyse e.V. an der Universit?t Rostock, Albert‐Einstein‐Strasse 29a, 18059 Rostock (Germany) |
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| Abstract: | A highly practical and general base‐catalyzed carbonylation of amines to the corresponding N‐formamides has been realized. Cheap inorganic bases, including Group IA and IIA metal hydroxides, alkoxides, carbonates, and phosphates, were effective catalysts for the transformation. In the presence of 10–40 mol % of KOH or K2CO3, various amines were converted into the corresponding N‐formamides in good‐to‐excellent yields using CO as the formylation reagents. |
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| Keywords: | amines base catalysis carbonylation formamides sustainable chemistry |
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