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Inside Cover: Seamless Integration of Dose‐Response Screening and Flow Chemistry: Efficient Generation of Structure–Activity Relationship Data of β‐Secretase (BACE1) Inhibitors (Angew. Chem. Int. Ed. 6/2014)
Authors:Dr. Michael Werner  Christoph Kuratli  Dr. Rainer E. Martin  Dr. Remo Hochstrasser  David Wechsler  Dr. Thilo Enderle  Dr. Alexander I. Alanine  Prof. Dr. Horst Vogel
Affiliation:1. Medicinal Chemistry, Small Molecule Research, Pharma Research & Early Development (pRED), F. Hoffmann‐La Roche AG, Grenzacherstrasse 124, 4070 Basel (Switzerland);2. Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology of Lausanne (EPFL), Station 6, 1015 Lausanne (Switzerland)
Abstract:
Keywords:biochemical assays  flow synthesis  lead discovery  medicinal chemistry  microfluidics
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