Towards High‐Performance Lewis Acid Organocatalysis |
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| Authors: | Dr. Lars Ratjen Manuel van Gemmeren Dr. Fabio Pesciaioli Prof. Dr. Benjamin List |
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| Affiliation: | Max‐Planck‐Institut für Kohlenforschung, Kaiser‐Wilhelm‐Platz 1, 45470 Mülheim an der Ruhr (Germany) |
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| Abstract: | The combination of Lewis acid organocatalysis and internal hydrogen‐bond assistance was used to develop a new type of highly active disulfonimide catalyst. The increased Lewis acidity was documented by activity comparisons as well as theoretical investigations. Finally, the potential of the hydrogen‐bond‐assisted disulfonimide catalyst was demonstrated by its application in an enantioselective transformation. |
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| Keywords: | catalyst design disulfonimides Lewis acids organocatalysis silylium ions |
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