Iridium‐Catalyzed Enantioselective CH Alkylation of Ferrocenes with Alkenes Using Chiral Diene Ligands |
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| Authors: | Prof. Dr. Takanori Shibata Tsubasa Shizuno |
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| Affiliation: | 1. Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University, Shinjuku, Tokyo 169‐8555 (Japan) http://www.chem.waseda.ac.jp/shibata/;2. ACT‐C, Japan Science and Technology Agency (JST), 4‐1‐8 Honcho Kawaguchi, Saitama, 332‐0012 (Japan) |
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| Abstract: | The first catalytic and enantioselective C? H alkylation of ferrocene derivatives with various alkenes was achieved. A cationic iridium complex, having a chiral diene ligand, and an isoquinolyl moiety as a directing group are essential for regioselective and enantioselective C? H bond activation. |
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| Keywords: | alkylation C H activation enantioselectivity iridium synthetic methods |
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