| 等温滴定量热法研究牛血清白蛋白与十二烷基二羟乙基甲基溴化铵的相互作用 |
| |
| 引用本文： | 胡晓环,童威,邵爽,雷群芳,方文军.等温滴定量热法研究牛血清白蛋白与十二烷基二羟乙基甲基溴化铵的相互作用[J].浙江大学学报(理学版),2011,38(5):525-529. |
| |
| 作者姓名： | 胡晓环 童威 邵爽 雷群芳 方文军 |
| |
| 作者单位： | 1. 浙江大学化学系,浙江杭州,310027
2. 浙江外国语学院化学系,浙江杭州,310012 |
| |
| 基金项目： | 国家自然科学基金资助项目(20673098,21073164); 浙江省自然科学基金资助项目(Y4080201) |
| |
| 摘 要： | 用等温滴定热量计测定了牛血清白蛋白（BSA）与十二烷基二羟乙基甲基溴化铵（DDHAB）的相互作用焓,探讨了表面活性剂浓度、温度和盐浓度等对相互作用焓的影响.BSA与表面活性剂相互作用焓是静电作用、去水化作用、疏水作用和表面活性剂胶束化等协同作用的结果,在其他条件保持不变时,相互作用焓随表面活性剂浓度改变,在临界胶束浓度（CMC）前后区域分别出现吸热峰.加入NaCl可引起相互作用焓峰值及其位置的变化.
|
| 关 键 词： | 等温滴定量热法 牛血清白蛋白 表面活性剂 相互作用 |
Isothermal titration calorimetric study on interactions between bovine serum albumin and N-dodecyl-di(2-hydroxyehtyl)-methyl ammonium bromide |
| |
| HU Xiao-huan,TONG Wei,SHAO Shuang,LEI Qun-fang,FANG Wen-jun.Isothermal titration calorimetric study on interactions between bovine serum albumin and N-dodecyl-di(2-hydroxyehtyl)-methyl ammonium bromide[J].Journal of Zhejiang University(Sciences Edition),2011,38(5):525-529. |
| |
| Authors: | HU Xiao-huan TONG Wei SHAO Shuang LEI Qun-fang FANG Wen-jun |
| |
| Institution: | HU Xiao-huan1,TONG Wei1,SHAO Shuang2,LEI Qun-fang1,FANG Wen-jun1(1.Department of Chemistry,Zhejiang University,Hangzhou 310027,China,2.Department of Chemistry,Zhejiang International Studies University,Hangzhou 310012,China) |
| |
| Abstract: | Interaction enthalpies between bovine serum albumin(BSA) and N-dodecyl-di(2-hydroxyehtyl)-methyl ammonium bromide(DDHAB) have been determined in an isothermal titration calorimeter.The influences of temperature,concentrations of surfactant and the added salt in the solutions on the interaction enthalpy have been discussed.The interaction enthalpies between BSA and a surfactant are resulted from the cooperative effects of electrostatic interaction,dehydration,hydrophobic interaction and surfactant micellizat... |
| |
| Keywords: | isothermal titration calorimetry(ITC) bovine serum albumin surfactant interaction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《浙江大学学报(理学版)》浏览原始摘要信息 |
| 点击此处可从《浙江大学学报(理学版)》下载免费的PDF全文 |
