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硅油基磁性流体作为玻璃体腔填充剂的初步研究(英文)
引用本文:龚雁,王正才,陆樟献,乔纳森·莱文,周子梅,周行涛,袁建树.硅油基磁性流体作为玻璃体腔填充剂的初步研究(英文)[J].宁波大学学报(理工版),2014(4):122-126.
作者姓名:龚雁  王正才  陆樟献  乔纳森·莱文  周子梅  周行涛  袁建树
作者单位:1. 宁波市第六医院,浙江 宁波,315040
2. 宁波职业技术学院,浙江 宁波,315800
3. 浙江万里学院,浙江 宁波,315101
4. 美国纽约布朗克斯黎巴嫩医院中心,纽约10451
5. 复旦大学附属眼耳鼻喉科医院,上海,200031
基金项目:Supported by Ningbo Natural Science Fundation(2010A610127;2013A610258);Ningbo Social Development Project(2010C50005)
摘    要:通过制备的硅油基磁性流体,将其注入猪的眼球内,在外磁场下观察流体在眼球内壁的运动行为,探究其作为填充剂的效果.研究结果表明:从磁性流体的实时运动行为中可以看出,在外磁场作用下磁性颗粒从硅油基磁性流体中分离出来,携带部分硅油移到磁场强度高的地方并覆盖其局部位置.实验结果为磁性液体作为新型玻璃体填充剂提供了一定的数据支持,在视网膜脱离修复中将有很好的应用前景.

关 键 词:玻璃体腔  硅油  磁流体

Preliminary Study:Silicone Oil Based Magnetic Fluid as A Vitreous Cavity Tamponade
GONG Yan,WANG Zheng-cai,LU Zhang-xian,Jonathan Levine,ZHOU Zi-mei,ZHOU Xing-tao,YUAN Jian-shu.Preliminary Study:Silicone Oil Based Magnetic Fluid as A Vitreous Cavity Tamponade[J].Journal of Ningbo University(Natural Science and Engineering Edition),2014(4):122-126.
Authors:GONG Yan  WANG Zheng-cai  LU Zhang-xian  Jonathan Levine  ZHOU Zi-mei  ZHOU Xing-tao  YUAN Jian-shu
Institution:GONG Yan, WANG Zheng-cai, LU Zhang-xian, Jonathan Levine, ZHOU Zi-mei, ZHOU Xing-tao, YUAN Jian-shu. ( 1 .Ningbo No.6 Hospital, Ningbo 315400, China; 2.Ningbo Polytechnic, Ningbo 315800, China; 3.Zhejiang Wanli University, Ningbo 315101, China; 4.Bronx Lebanon Hospital Center, NY 10451, USA; 5.Shanghai Eye & ENT Hospital of Fudan University, Shanghai 200032, China )
Abstract:The paper aims at investigating the potential application of silicone oil based Fe3O4 magnetic fluid as a vitreous tamponade agent. The silicone oil based Fe3O4 magnetic fluid is prepared and deposited in a pig eye. An external magnetic field is applied to the eye to test the behavior of the fluid in vitro as well as the tamponade effect of the magnetic fluid. In the vitro study, it shows that under the influence of an external magnet, the magnetic Fe3O4 micelles are separated from silicone oil toward the maximum magnetic field strength(toward the magnet) and coated on the inner scleral wall evenly in that area. The experiment result provides the preliminary data supporting silicone oil based Fe3O4 magnetic nanoparticles as a novel vitreous tamponade agent, especially in the case of inferior retinal detachments.
Keywords:vitreous cavity  silicone oil  magnetic fluids
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