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MaxSynBio: Avenues Towards Creating Cells from the Bottom Up |
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| Authors: | Prof?Dr Petra Schwille Prof?Dr Joachim Spatz Prof?Dr Katharina Landfester Prof?Dr Eberhard Bodenschatz Prof?Dr Stephan Herminghaus Prof?Dr Victor Sourjik Dr Tobias J Erb Prof?Dr Philippe Bastiaens Prof?Dr Reinhard Lipowsky Prof?Dr Anthony Hyman Prof?Dr Peter Dabrock Dr Jean‐Christophe Baret Dr Tanja Vidakovic‐Koch Dr Peter Bieling Dr Rumiana Dimova Dr Hannes Mutschler Dr Tom Robinson Dr T‐Y Dora Tang Dr Seraphine Wegner Prof?Dr Kai Sundmacher |
| Institution: | 1. Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Martinsried, Germany;2. MPI for Medical Research, Heidelberg, Germany;3. MPI for Polymer Research, Mainz, Germany;4. MPI for Dynamics and Self-Organization, G?ttingen, Germany;5. MPI for Terrestrial Microbiology, Marburg, Germany;6. MPI for Molecular Physiology, Dortmund, Germany;7. MPI of Colloids and Interfaces, Potsdam, Germany;8. MPI of Molecular Cell Biology and Genetics, Dresden, Germany;9. Friedrich-Alexander University Erlangen-Nuremberg, Department of Theology, Erlangen, Germany;10. University of Bordeaux -Centre de Recherches Paul Pascal, Pessac, France;11. Process Systems Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany |
| Abstract: | A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom‐up approach to synthetic biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non‐living components. The fundamental insights gained from the activities in MaxSynBio could eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace the natural cells currently used in conventional biotechnology. |
| Keywords: | biotechnology bottom-up design microfluidics protocells synthetic biology |