Palladium‐Catalyzed Asymmetric Reductive Heck Reaction of Aryl Halides |
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| Authors: | Guizhou Yue Kaining Lei Hajime Hirao Jianrong Zhou |
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| Institution: | 1. Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore);2. College of Science, Sichuan Agricultural University, Ya'an, Sichuan, 625014 (China) |
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| Abstract: | Asymmetric reductive Heck reaction of aryl halides is realized in high stereoselectivity. Hydrogen‐bond donors, trialkylammonium salts in a glycol solvent, were used to promote halide dissociation from neutral arylpalladium complexes to access cationic, stereoselective pathways. |
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| Keywords: | asymmetric catalysis hydrogen bonding olefins palladium synthetic methods |
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