Hydroaminomethylation Beyond Carbonylation: Allene–Imine Reductive Coupling by Ruthenium‐Catalyzed Transfer Hydrogenation |
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| Authors: | Susumu Oda Brannon Sam Prof Michael J Krische |
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| Institution: | University of Texas at Austin, Department of Chemistry, 105 E 24th St. (A5300), Austin, TX 78712‐1167 (USA) |
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| Abstract: | Ruthenium(II)‐catalyzed hydrogen transfer from 2‐propanol mediates reductive coupling of 1,1‐disubstituted allenes with formaldimines with complete branch‐regioselectivity, thus representing a new method for hydroaminomethylation beyond classical hydroformylation/reductive amination. |
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| Keywords: | allenes green chemistry ruthenium synthetic methods transfer hydrogenation |
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