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Transfer of Two‐Dimensional Oligonucleotide Patterns onto Stereocontrolled Plasmonic Nanostructures through DNA‐Origami‐Based Nanoimprinting Lithography |
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| Authors: | Yinan Zhang Prof Jie Chao Prof Huajie Liu Fei Wang Prof Shao Su Bing Liu Prof Lan Zhang Dr Jiye Shi Prof Lihua Wang Prof Wei Huang Prof Lianhui Wang Prof Chunhai Fan |
| Institution: | 1. Key Laboratory for Organic Electronics & Information Displays (KLOEID), Institute of Advanced Materials (IAM) and School of Materials Science and Engineering, Nanjing University of Posts & Telecommunications Institution, Nanjing, China;2. Division of Physical Biology and Bioimaging Center, Shanghai Synchrotron Radiation Facility, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China;3. Kellogg College, University of Oxford, Oxford, UK;4. UCB Pharma, Slough, UK |
| Abstract: | The precise functionalization of self‐assembled nanostructures with spatial and stereocontrol is a major objective of nanotechnology and holds great promise for many applications. Herein, the nanoscale addressability of DNA origami was exploited to develop a precise copy‐machine‐like platform that can transfer two‐dimensional oligonucleotide patterns onto the surface of gold nanoparticles (AuNPs) through a deliberately designed toehold‐initiated DNA displacement reaction. This strategy of DNA‐origami‐based nanoimprinting lithography (DONIL) demonstrates high precision in controlling the valence and valence angles of AuNPs. These DNA‐decorated AuNPs act as precursors in the construction of discrete AuNP clusters with desired chirality. |
| Keywords: | DNA nanotechnology gold nanoimprinting lithography nanoparticles self-assembly |