Synthesis and In Vitro Antibacterial Activities of Novel 2‐Aryl‐3‐(phenylamino)‐2,3‐dihydroquinazolin‐4(1H)‐one Derivatives |
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| Authors: | Ali A Mohammadi Hamed Rohi Ali Abolhasani Soorki |
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| Institution: | 1. Department of Chemistry, Sabzevar Branch, Islamic Azad University, , Sabzevar, Iran;2. Faculty of Science, Department of Chemistry, Ferdosy University, , Mashad, Iran;3. Shaheed Beheshti University, Academic Center for Education, Culture, and Research, Research Institute of Applied Sciences, , Tehran, Iran |
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| Abstract: | An efficient synthesis of novel 2‐aryl‐3‐(phenylamino)‐2,3‐dihydroquinazolin‐4(1H)‐one derivatives using KAl(SO4)2.12H2O (Alum) as a catalyst from an aldehyde and 2‐amino‐N‐phenylbenzohydrazine in ethanol is described. All synthesized derivatives were screened for anti‐bacterial activity. Some compounds exhibited promising anti‐bacterial activity with reference to standard antibiotics. |
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