A Facile and Efficient Solid Supported,One‐Pot Synthesis of Functionalized Piperidine Derivatives Catalyzed by Amberlite IRA400‐Cl Resin/I2/KI via Multicomponent Reaction |
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| Authors: | Gurusamy Harichandran Savarimuthu David Amalraj Ponnusamy Shanmugam |
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| Institution: | 1. Department of Polymer Science, University of Madras, , Chennai, 600 025 India;2. Organic Chemistry Laboratory, Central Leather Research Institute, , Chennai, 600 020 India |
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| Abstract: | A facile and efficient one‐pot, solid supported synthesis of functionalized piperidine derivatives catalyzed by Amberlite IRA400‐Cl resin/I2/KI via a multicomponent reaction of various aldehydes, aromatic amines, and 1,3‐dicarbonyl compounds has been achieved. The reaction has been carried out in a one‐pot reaction and Amberlite resin as a solid supported catalyst at room temperature. Shorter reaction time, easy workup, yield, and mild reaction condition make the novel synthetic strategy both practical and attractive. |
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| Keywords: | Piperidine derivatives Multi‐component reaction Amberlite resin Solid supported |
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