Synthesis and Biological Activities of Novel 6‐Alkylamino‐11,12‐dihydro‐11‐arylbenzo[c]phenanthridine Derivatives |
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| Authors: | Min Zhang Li Liu Huifeng Xiao Ting Zhao Liuqing Yang Xiaohua Xu |
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| Institution: | 1. School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, China;2. State Key Laboratory and Institute of Elemento‐Organic Chemistry, Nankai University, Tianjin, China |
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| Abstract: | A series of novel benzoc]phenanthridine derivatives 2a , 2b , 2c , 2d , 2e , 2f , 2g , 2h , 2i , 2j , 2k , 2l , 2m and 3a , 3b , 3c , 3d , 3e , 3f bearing an alkylamino side chain at their 6‐position were synthesized. All of the target compounds were confirmed by 1H NMR, 13C NMR, and HRMS, and some of them were also characterized by IR and 19F NMR. The preliminary bioassays showed that the target compounds displayed fungicidal activities; for example, compound 2l showed 60.0% and 70.0% inhibitive activity against Alternaria solani and Cercospora arachidicola at 50 mg/L, respectively, and some compounds also displayed plant growth‐regulating activities. |
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