Chemospecific chromium[VI] catalyzed oxidation of C-H bonds at -40 degrees C1 |
| |
Authors: | Lee Seongmin Fuchs P L |
| |
Institution: | Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA. |
| |
Abstract: | H5IO6 in the presence of catalytic chromoyl diacetate is a powerful method for oxidation of C-H bonds. Tertiary and oxygen activated C-H bonds are oxidized to tertiary alcohols or ketones at temperatures as low as -40 degrees C. The putative reagent is neutral dioxoperoxy chromiumVI] which undergoes C-H oxidation with retention of stereochemistry. This reagent appears to be the first reagent capable of oxidation of a C-H bond in the presence of an olefin without concomitant epoxidation. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|