Facile synthesis of cucurbit[n]uril derivatives via direct functionalization: expanding utilization of cucurbit[n]uril |
| |
| Authors: | Jon Sang Yong Selvapalam Narayanan Oh Dong Hyun Kang Jin-Koo Kim Soo-Young Jeon Young Jin Lee Jae Wook Kim Kimoon |
| |
| Institution: | National Creative Research Initiative Center for Smart Supramolecules and Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang 790-784, Republic of Korea. |
| |
| Abstract: | A long-standing problem in cucurbituril chemistry is answered through the first direct functionalization of cucurbitn]uril (CBn]; n = 5-8)) leading to perhydroxyCBn] which can be further modified to provide tailored CBn] derivatives with desired functional groups and good solubility. Anchoring a CB6] derivative on the surface and its potential application as a sensor are demonstrated. A CB6] derivative forms nanospheres with possible use in protein and peptide drug delivery. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
