Organocatalytic enantioselective Friedel-Crafts reaction of pyrrole derivatives with imines |
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| Authors: | Li Guilong Rowland Gerald B Rowland Emily B Antilla Jon C |
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| Institution: | Department of Chemistry, University of South Florida, 4202 East Fowler Avenue CHE205A, Tampa, Florida 33620, USA. |
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| Abstract: | A highly enantioselective Friedel-Crafts reaction of pyrrole derivatives with N-acyl imines catalyzed by chiral phosphoric acids was developed. The reactions produced the pyrrole derivatives in high yields and enantioselectivity. |
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