|
|||||
|
|
SnCl4/SiO2: An Efficient Heterogeneous Alternative for One‐Pot Synthesis of β‐Acetamidoketones |
|
| Authors: | Bi Bi Fatemeh Mirjalili Mohammad M Hashemi Bahareh Sadeghi Hamideh Emtiazi |
| Institution: | 1. Department of Chemistry, College of Science, Yazd, University, Yazd, P.O. Box 89195‐741, Iran;2. Department of Chemistry, Sharif University of Technology, P.O. Box 11365‐9516, Tehran, Iran;3. Faculty of Chemistry, Islamic Azad University, Science and Research Campus, Tehran, Iran |
| Abstract: | Enolizable ketones have been reacted in a one‐pot method with aromatic aldehydes, acetyl chloride and acetonitrile at room temperature in the presence of SnCl4/SiO2 to furnish the corresponding β‐acet‐amidoketones in improved yields. Acetylation of an aromatic hydroxyl group was observed while using 4‐hydroxybenzaldehyde or vanillin and the corresponding β‐acetamidoketones were isolated in an excellent yield. |
| Keywords: | Tin chloride (SnCl4) β ‐Acetamidoketones One‐pot synthesis SnCl4/SiO2 |