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The Reaction of 2-Methylindole with Pyruvic Acid
Authors:Sheng-Hsu Zee  Sheng-Yunn Lin  Tei-Min Fin
Abstract:The reaction of 2-methylindole with pyruvic acid was studied. Two products are found to be depending on experimental conditions, including the 2:2 condensation adduct and the 2:1 condensation adduct. The reaction mechanism evidently involves a 1:1 adduct of 2-hydroxy-2-(2-methylindol-3-yl)-propionic acid as an intermediate.
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