|
|||||
|
|
Traceless chemical ligations from O-acyl serine sites |
|
| Authors: | El Khatib Mirna Elagawany Mohamed Jabeen Farukh Todadze Ekaterina Bol'shakov Oleg Oliferenko Alexander Khelashvili Levan el-Feky Said A Asiri Abdullah Katritzky Alan R |
| Institution: | Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. |
| Abstract: | Chemical ligation via O- to N-acyl transfer of O-acylated serine containing peptides affords serine containing native peptides via 8- and 11-membered cyclic transition states opening the door to a wide variety of potential applications to peptide elaboration. The feasibility of these traceless chemical ligations is feasible as supported by computation. |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |