Determination of blood glucose parameter from human blood serum by using a quartz crystal microbalance sensor coated with phthalocyanines compounds |
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| Authors: | Evin AH&#x;N SADIK Hamdi Melih SARAOLU &#x;lke GÜROL Mehmet Ali EBEOLU Fatma Emel KOAK |
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| Institution: | 1. Electrical and Electronics Engineering Department, Faculty of Engineering, Kütahya Dumlupınar University, Kütahya, TURKEY ; 2. Institute of the Marmara Research Center of the Scientific and Technological Research Council of Turkey, Kocaeli, Turkey ; 3. Department of Medical Biochemistry, Kütahya Health Sciences University, Kütahya, TURKEY |
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| Abstract: | Determining the blood glucose level is important for the prevention and treatment of diabetes mellitus. We developed a sensor system using Quartz Crystal Microbalance (QCM) to determine the blood glucose level from human blood serum. This study consists of two experimental stages: artificial glucose/pure water solution tests and human blood serum tests. In the first stage of the study, the QCM sensor with the highest performance was identified using artificial glucose solution concentrations. In the second stage of the study, human blood serum measurements were performed using QCM to determine blood glucose levels. QCM sensors were coated with phthalocyanines (Pcs) by jet spray method. The blood glucose values of 96 volunteers, which ranged from 71 mg/dL to 329 mg/dL, were recorded. As a result of the study, human glucose values were determined with an average error of 3.25%. |
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| Keywords: | Phthalocyanines blood glucose human blood serum liquid sensing quartz crystal microbalance |
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